1.

Record Nr.

UNINA9910349455903321

Autore

Pstras Leszek

Titolo

Mathematical Modelling of Haemodialysis : Cardiovascular Response, Body Fluid Shifts, and Solute Kinetics / / by Leszek Pstras, Jacek Waniewski

Pubbl/distr/stampa

Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019

ISBN

3-030-21410-9

Edizione

[1st ed. 2019.]

Descrizione fisica

1 online resource (156 pages)

Disciplina

617.461059

583.44

Soggetti

Biomedical engineering

Biomathematics

Cardiovascular system

Biomedical Engineering/Biotechnology

Physiological, Cellular and Medical Topics

Biomedical Engineering and Bioengineering

Cardiovascular Biology

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di contenuto

Introduction to renal replacement therapies and mathematical modelling in physiology -- Mathematical modelling in physiology -- Model structure, equations and parameters -- Model analysis and validation -- Simulation results and model outcomes -- Conclusions, challenges and future research directions.

Sommario/riassunto

Beginning with an introduction to kidney function, renal replacement therapies, and an overview of clinical problems associated with haemodialysis, this book explores the principles of the short-term baroreflex regulation of the cardiovascular system and the mechanisms of water and solute transport across the human body from a mathematical model perspective. It synthesizes theoretical physiological concepts and practical aspects of mathematical modelling needed for simulation and quantitative analysis of the haemodynamic response to dialysis therapy. Including an up-to-date review of the



literature concerning the modelled physiological mechanisms and processes, the book serves both as an overview of transport and regulatory mechanisms related to the cardiovascular system and body fluids and as a useful reference for the study and development of mathematical models of dynamic physiological processes. Mathematical Modelling of Haemodialysis: Cardiovascular Response, Body Fluid Shifts, and Solute Kinetics is intended for researchers and graduate students in biomedical engineering, physiology, or medicine interested in mathematical modelling of cardiovascular dynamics and fluid and solute transport across the human body, both under physiological conditions and during haemodialysis therapy.