1.

Record Nr.

UNINA9910349443103321

Autore

Koo Kevin M

Titolo

Advancing Gene Fusion Detection Towards Personalized Cancer Nanodiagnostics           / / by Kevin M. Koo

Pubbl/distr/stampa

Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019

ISBN

3-030-31000-0

Edizione

[1st ed. 2019.]

Descrizione fisica

1 online resource (XIII, 102 p.)

Collana

Springer Theses, Recognizing Outstanding Ph.D. Research, , 2190-5053

Disciplina

610.28

Soggetti

Biomedical engineering

Nanotechnology

Cancer research

Biomedical Engineering/Biotechnology

Biomedical Engineering and Bioengineering

Cancer Research

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di contenuto

Unifying Next-Generation Biomarkers and Nanodiagnostic Platforms for Precision Prostate Cancer (PCa) Management -- Colorimetric Gene Fusion Diagnostics for Visual Binary Readout -- Label –Free Surface-Enhanced Raman Scattering Detection System for Clinical Biomarker Targets -- Amplification-Free Electrochemical RNA Biomarker Sensing -- Simultaneous Analysis of Multiple Biomarkers via High-Throughput Parallel Profiling.

Sommario/riassunto

This book presents a unique concept of merging nanotechnology and novel urinary biomarkers for accurate early prostate cancer detection, discussing an entire progressive pipeline of innovative new strategies in biosensor development, from a simple colorimetric system to a complex system for simultaneous multiple biomarker sensing. For newcomers to the field of nucleic acid biosensing, it also describes various isothermal amplification and amplification-free strategies, which are currently the main research areas. Lastly, the book introduces and demonstrates the notion of clinical nanobiosensor



validation toward clinical translation: the ultimate aim of researchers in the biosensor field. This book is a valuable reference resource learners seeking inspiration for cancer biosensor development.