1.

Record Nr.

UNINA9910349438403321

Titolo

Pluripotent Stem Cells in Eye Disease Therapy / / edited by Kapil Bharti

Pubbl/distr/stampa

Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019

ISBN

3-030-28471-9

Edizione

[1st ed. 2019.]

Descrizione fisica

1 online resource (210 pages)

Collana

Advances in Experimental Medicine and Biology, , 0065-2598 ; ; 1186

Disciplina

616.02774

Soggetti

Stem cells

Regenerative medicine

Tissue engineering

Biomedical engineering

Ophthalmology

Stem Cells

Regenerative Medicine/Tissue Engineering

Biomedical Engineering/Biotechnology

Oftalmopaties

Cèl·lules mare

Llibres electrònics

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Pluripotent Stem Cells to Model Degenerative Retinal Diseases: The RPE perspective -- Utility of induced pluripotent stem cell-derived retinal pigment epithelium for an in vitro model of proliferative vitreoretinopathy -- Developing cell-based therapies for RPE-associated degenerative eye diseases -- Pluripotent Stem Cell derived 3D Ocular Tissue Transplantation – role of immune system in cell integration -- Use of Stem Cells to model optic nerve degeneration diseases -- Surgical approaches for RPE/retina -- 3D Engineering Ocular Tissues for Disease Modeling and Drug Testing -- Index.

Sommario/riassunto

This book discusses applications of pluripotent stem cells to study eye disease in vitro and to create novel therapies for degenerative eye diseases. Chapters are contributed by experts in the field and cover



such topics as the use of pluripotent stem cells in 2D and 3D engineering of ocular tissues for disease modelling and drug testing as well as approaches to replace degenerated RPE and photoreceptors in macular degeneration and retinitis pigmentosa. Pluripotent Stem Cells in Eye Disease Therapy presents a comprehensive discussion of basic science and clinical applications and is an indispensable resource for everyone from advanced graduate students to advanced professionals who want to learn about the potential of stem cell biology and its role in the field of retinal diseases. .