1.

Record Nr.

UNINA9910816761103321

Titolo

Chiral drugs : chemistry and biological action / / edited by Guo-Qiang Lin, Qi-Dong You, Jie-Fei Cheng

Pubbl/distr/stampa

Hoboken, N.J. : , : Wiley, , 2011

©2011

ISBN

9786613239839

9781283239837

1283239833

9781118075630

1118075633

9781118075647

1118075641

9781118075623

1118075625

Edizione

[1st ed.]

Descrizione fisica

1 online resource (x, 456 pages) : illustrations

Altri autori (Persone)

LinGuo-Qiang <1943->

YouQi-Dong

ChengJie-Fei

Disciplina

615/.19

Soggetti

Chiral drugs

Drug development

Structure-activity relationships (Biochemistry)

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Machine generated contents note: Chapter 1. Overview of chirality and chiral drugs (Guo-Qiang Lin, Jiange Zhang and Jie-Fei Cheng). -- Chapter 2. Chiral drugs through asymmetric synthesis (Guo-Quiang Lin and Xing-Wen Sun). -- Chapter 3. Chiral drugs via biocatalytical approaches (Jianqiang Wang and Wenya Lu). -- Chapter 4. Chiral resolution (Qi-Dong You). -- Chapter 5. Fluorine-containing chiral drugs (Xiao-Long Qiu, Xuyi Yue and Feng-Ling Qing). -- Chapter 6. Industrial application of chiral technologies (Hui-Ying (Harry) Li, Rui Liu, Carl Behrens, and Chao-Ying Ni). -- Chapter 7. Computation



modeling study on mechanism-of-action of chiral drugs (Deping Wang and Eric Gu). -- Chapter 8. Pharmacology of chiral drugs (Yongge Liu and Xiao-Hui Gu). -- Chapter 9. Pharmacokinetics of chiral drugs (Hanqing Dong, Xiaochuan Guo and Zengbiao Li). -- Chapter 10. Toxicology of chiral drugs (Guang Yang and Hai-Zhi Bu). -- Chapter 11. Representative chiral drugs (Jiangqin Sun, Dingguo Liu and Zhimin Wang).

Sommario/riassunto

"This book overviews chiral drugs and their impact in the pharmaceutical industry. The chapters detail basics and trends in chiral drug discovery and development, as well as techniques / skills and trends of asymmetric synthesis. The first section introduces the general concept of chirality and its impact on the drug discovery and development. This part includes history of chiral drug development, key technologies for preparation of chiral drugs, and industrial applications of chiral technologies"--Provided by publisher.

2.

Record Nr.

UNINA9910346782303321

Autore

Schönbein Miriam

Titolo

Omnidirectional Stereo Vision for Autonomous Vehicles

Pubbl/distr/stampa

KIT Scientific Publishing, 2014

ISBN

1000046298

Descrizione fisica

1 online resource (XV, 125 p. p.)

Collana

Schriftenreihe / Institut für Mess- und Regelungstechnik, Karlsruher Institut für Technologie

Soggetti

Technology: general issues

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Sommario/riassunto

Environment perception with cameras is an important requirement for many applications for autonomous vehicles and robots. This work presents a stereoscopic omnidirectional camera system for autonomous vehicles which resolves the problem of a limited field of view and provides a 360° panoramic view of the environment. We present a new projection model for these cameras and show that the



camera setup overcomes major drawbacks of traditional perspective cameras in many applications.