1.

Record Nr.

UNINA9910346753603321

Autore

Brian H. Smith

Titolo

Biogenic Amines and Neuromodulation of Animal Behavior, 2nd Edition

Pubbl/distr/stampa

Frontiers Media SA, 2018

Descrizione fisica

1 online resource (238 p.)

Collana

Frontiers Research Topics

Soggetti

Neurosciences

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Sommario/riassunto

Since Erspamer and Boretti, 1951 first described the biogenic amine octopamine in the octopus salivary gland as a molecule with "adrenaline-like" action, decades of extensive studies demonstrated the important role octopamine and its precursor tyramine play in invertebrate physiology and behavior. This book contains the latest original research papers on tyramine/octopamine and their receptors in different neuronal and non-neuronal circuits of insects. </p>Additonally, this book elucidates in detail the latest research on the function of other biogenic amines and their receptors, such as dopamine and serotonin in insects and mice. The reviews in this book summarize the most recent research on the role of biogenic amines in insect antennae, synaptic development, and behavioral modulation by spontaneous dopamine release in Drosophila. Finally, one perspective paper discusses the evolution of social behavior and biogenic amines. <br><br>We recommend this book for all scholars interested in the latest advanced research on the role of biogenic amines in animal behavior. <br><br>ITS dedicates the topic to her teacher, Plotnikova Svetlana Ivanovna (1922-2013).



2.

Record Nr.

UNINA9910557702003321

Autore

Cuenda Ana

Titolo

P38 Signaling Pathway

Pubbl/distr/stampa

Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021

Descrizione fisica

1 online resource (194 p.)

Soggetti

Research and information: general

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Sommario/riassunto

p38 Mitogen activated protein kinases (p38MAPK) are a group of evolutionary conserved protein kinases which are central for cell adaptation to environmental changes as well as for immune response, inflammation, tissue regeneration and tumour formation. The interest in this group of protein kinases has grown continually since their discovery. Recent studies using new genetic and pharmacological tools are providing helpful information on the function of these stress-activated protein kinases and show that they have an acute impact on the development of prevalent diseases related to inflammation, diabetes, neurodegeneration, and cancer. In this Special Issue we present novel advances and review the knowledge on the identification of p38MAPK substrates, functions, and regulation; mechanisms underlying the role of p38MAPK in malignant transformation and other pathologies; and therapeutic opportunities associated with regulation of p38MAPK activity.