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1. |
Record Nr. |
UNISALENTO991003780469707536 |
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Autore |
Sykes, Karen Margaret |
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Titolo |
Arguing with anthropology : an introduction to critical theories of the gift / Karen Sykes |
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Pubbl/distr/stampa |
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London ; New York : Routledge, 2005 |
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ISBN |
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Descrizione fisica |
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x, 244 p. : ill., c. geogr. ; 24 cm |
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Disciplina |
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Soggetti |
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Doni |
Antropologia culturale |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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2. |
Record Nr. |
UNINA9910694559403321 |
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Autore |
Farr Warner D |
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Titolo |
The third temple's holy of holies [[electronic resource] ] : Israel's nuclear weapons / / Warner D. Farr |
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Pubbl/distr/stampa |
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Maxwell Air Force Base, Ala. : , : USAF Counterproliferation Center, Air War College, Air University, , [1999] |
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Collana |
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Counterproliferation papers. Future warfare series ; ; no. 2 |
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Soggetti |
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Nuclear weapons - Israel |
Nuclear weapons - Israel - History |
Israel Military policy |
Israel Foreign relations United States History |
United States Foreign relations Israel History |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Title from title screen (viewed on Aug. 23, 2005). |
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Nota di bibliografia |
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Includes bibliographical references. |
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Nota di contenuto |
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Abstract -- Introduction -- 1948-1962: With French cooperation -- 1963-1973: Seeing the project through to completion -- 1974-1999: Bringing the bomb up the basement stairs -- Appendix: Estimates of the Israeli nuclear arsenal. |
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Sommario/riassunto |
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This paper is a history of the Israeli nuclear weapons program drawn from a review of unclassified sources ... Israel has most probably conducted several nuclear bomb tests. They have continued to modernize and vertically proliferate and are now one of the world's larger nuclear powers. Using 'bomb in the basement' nuclear opacity, Israel has been able to use its arsenal as a deterrent to the Arab world while not technically violating American nonproliferation requirements. |
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3. |
Record Nr. |
UNINA9910337952803321 |
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Autore |
Garrido Federico |
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Titolo |
MHC Class-I Loss and Cancer Immune Escape / / by Federico Garrido |
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Pubbl/distr/stampa |
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Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
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ISBN |
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Edizione |
[1st ed. 2019.] |
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Descrizione fisica |
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1 online resource (109 pages) : illustrations |
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Collana |
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Advances in Experimental Medicine and Biology, , 0065-2598 ; ; 1151 |
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Disciplina |
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Soggetti |
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Cancer - Research |
Molecular biology |
Immunology |
Human genetics |
Cancer Research |
Molecular Medicine |
Human Genetics |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di contenuto |
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Preface -- Introduction -- Mhc/Hla Class I Loss In Cancer Cells -- Hla |
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Class-I Expression And Cancer Immunotherapy -- Hla Class-Ii Expression In Human Tumors -- Index. |
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Sommario/riassunto |
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This book is about the escape strategies used by cancer cells to avoid the immune response of the host. The main characters of this story are the “Antigen Presenting Molecules” and the “T Lymphocytes”. The former are known as the Major Histocompatibility Complex (MHC): the H-2 and the HLA molecules. The latter are a subgroup of white cells travelling all over our body which are capable to distinguish between “self and non self”. Readers will know from the inside about the history of the HLA genetic system and will discover how T lymphocytes recognize and destroy cancer cells. One of the key important questions is: Why tumors arise, develop and metastasize? This book tries to answer this question and will explain how cancer cells become invisible to killer T lymphocytes. The loss of the HLA molecules is a major player in this tumor escape mechanism. Cancer immunotherapy is aimed at stimulating T lymphocytes to destroy tumor cells. However, the clinical response rate is not as high as expected. The molecular mechanisms responsible for MHC/HLA antigen loss play a crucial role in this resistance to immunotherapy. This immune escape mechanism will be discussed in different types of tumors: lung, prostate, bladder and breast…ect. as well as melanoma and lymphoma. This book will be useful to Oncologists, Pathologists and Immunologist that will enter this fascinating area of research. It will be also interesting for biologist, doctoral students and medical residents interested in “Tumor Immunology”. . |
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