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Record Nr. |
UNINA9910337949603321 |
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Titolo |
Cholesterol Modulation of Protein Function : Sterol Specificity and Indirect Mechanisms / / edited by Avia Rosenhouse-Dantsker, Anna N. Bukiya |
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Pubbl/distr/stampa |
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Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
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ISBN |
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Edizione |
[1st ed. 2019.] |
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Descrizione fisica |
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1 online resource (200 pages) |
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Collana |
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Advances in Experimental Medicine and Biology, , 0065-2598 ; ; 1115 |
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Disciplina |
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Soggetti |
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Proteomics |
Proteins |
Cell membranes |
Molecular biology |
Protein Science |
Membrane Biology |
Molecular Medicine |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di contenuto |
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Part 1. Sterol specificity in modulating protein function: 1. Chirality effect on cholesterol modulation of protein function -- 2. A critical analysis of molecular mechanisms underlying membrane cholesterol sensitivity of GPCRs -- 3. Regulation of BK channel activity by cholesterol and its derivatives -- 4. Chiral specificity of cholesterol orientation within cholesterol binding sites in inwardly rectifying potassium channels -- Part 2. Indirect modulation of protein function by cholesterol: 5. Cholesterol effect on the physical properties of lipid membranes -- 6. Effect of cholesterol on the dipole potential of lipid membranes -- 7. Mass spectroscopy imaging of cholesterol -- 8. Cholesterol-dependent gating effects on ion channels. |
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Sommario/riassunto |
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In this book, renowned scientists describe the role of steroid chirality and modification of lipid membrane physical properties in the modulation of G protein-coupled receptors and ion channels. The |
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