1.

Record Nr.

UNINA9910337514103321

Titolo

Textbook of Autoinflammation / / edited by Philip J. Hashkes, Ronald M. Laxer, Anna Simon

Pubbl/distr/stampa

Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019

ISBN

3-319-98605-8

Edizione

[1st ed. 2019.]

Descrizione fisica

1 online resource (X, 820 p. 154 illus., 135 illus. in color.)

Disciplina

616.978

Soggetti

Rheumatology

Pediatrics

Immunology

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Part 1. Basic Science and Biology of Autoinflammation -- Part 2: Autoinflammatory Diseases -- Part 3: Integrative Cross Disease -- Part 4: Pharmacology and Therapies -- Part 5: Measurement and Data Analysis in Autoinflammatory Disease.

Sommario/riassunto

This book, the first complete textbook on this novel field in Medicine, comprehensively covers the clinical presentation, pathogenesis, genetics, and latest management strategies for autoinflammatory disorders as well as the basic science of autoinflammation. Relevant concepts such as how translational science of genetics and immunology relates to the innate immune system and autoinflammation are covered. Descriptions of the monogenic and polygenic/complex diseases that fall under the umbrella of autoinflammatory diseases are provided. Further topics covered include the latest clinical and genetic diagnostic approaches, concepts on the relationship between autoinflammation and autoimmunity/immunodeficiency, the role of autoinflammation in cancer, treatments and management strategies for these diseases, and potential areas of future development. The Textbook of Autoinflammation systematically describes and reviews diagnostic and treatment options for autoinflammatory disorders as well as all aspects of the concept of autoinflammation, and represents a valuable resource



for professionals in a variety of disciplines who encounter these patients or who study autoinflammation.