1.

Record Nr.

UNINA9910309857803321

Titolo

Biological Robustness : Emerging Perspectives from within the Life Sciences / / edited by Marta Bertolaso, Silvia Caianiello, Emanuele Serrelli

Pubbl/distr/stampa

Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018

ISBN

3-030-01198-4

Edizione

[1st ed. 2018.]

Descrizione fisica

1 online resource (X, 258 p. 26 illus., 15 illus. in color.)

Collana

History, Philosophy and Theory of the Life Sciences, , 2211-1956 ; ; 23

Disciplina

570.1

572.838

Soggetti

Biology - Philosophy

Bioinformatics

Neurosciences

Philosophy of nature

Philosophy of Biology

Computational and Systems Biology

Neuroscience

Philosophy of Nature

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di contenuto

1. Introduction: Is Biological Robustness Unique? -- 2. Robustness, Mechanism, and the Counterfactual use of Goal-directedness in Biology (Marco Buzzoni) -- 3. Difference (Alfredo Marcos) -- 4. Robustness and Autonomy (Alvaro Moreno) -- 5. Robustness as an Explanandum and Explanans in Evolutionary Biology and Ecology (Philippe Hunemann) -- 6. Issues in Developmental Robustness (Manfred D. Laubichler) -- 7. Physical Robustness and Biological Robustness: Dynamical Rearrangement of Symmetry and Minimum Stimulus (Giuseppe Vitiello) -- 8. News from the ‘Twilight Zone’: Protein Molecules Between the Crystal and the Fluid (Alessandro Giuliani) -- 9. Robustness and Emergent Dynamics in Noisy Biological Systems (Simonetta Filippi) -- 10. Robustness in Neurological Systems (Sandra D. Mitchell) -- 11. Robustness Notions and Physiological Adaptability: Philosophical and



Biomedical Reflections on the Neurological Basis of Disorders (Raffaella Campaner) -- 12. Reconciling Variability with Robust Behavior at Single-neuron Level (Timothy O’Leary) -- 13. Functional Connectivity, Regulation, and SOM Interneurons Spontaneous Activity (Alison Barth) -- 14. Temporal Organization and Robustness in Neural Systems (Trey Boone) -- 15. Muscle Synergies: Concept, Principles, and Potential use in Neurorehabilitation Module (Emilio Bizzi) -- 16. Robustness of Musical Language: The Role of Motor Systems (Flavio Keller) -- 17. Conclusion - The Upcoming Role of Robustness in Biology. .

Sommario/riassunto

This volume reviews examples and notions of robustness at several levels of biological organization. It tackles many philosophical and conceptual issues and casts an outlook on the future challenges of robustness studies in the context of a practice-oriented philosophy of science. The focus of discussion is on concrete case studies. These highlight the necessity of a level-dependent description of robust biological behaviors.Experts from the neurosciences, biochemistry, ecology, biology, and the history and the philosophy of life sciences provide a multiplex perspective on the topic. Contributions span from protein folding, to cell-level robustness, to organismal and developmental robustness, to sensorimotor systems, up to the robustness of ecological systems.Several chapters detail neurobiological case-studies. The brain, the poster child of plasticity in biology, offers multiple examples of robustness. Neurobiology explores the importance of temporal organization and multiscalarity in making this robustness-with-plasticity possible. The discussion also includes structures well beyond the brain, such as muscles and the complex feedback loops involved in the peculiar robustness of music perception. Overall, the volume grounds general reflections upon concrete case studies, opening to all the life sciences but also to non-biological and bio-inspired fields such as post-modern engineering. It will appeal to researchers, students, as well as non-expert readers.