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Record Nr. |
UNINA9910261136003321 |
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Autore |
Emanuela Marcenaro |
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Titolo |
NK Cell Subsets in Health and Disease: New Developments |
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Pubbl/distr/stampa |
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Descrizione fisica |
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1 online resource (243 p.) |
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Collana |
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Frontiers Research Topics |
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Soggetti |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Sommario/riassunto |
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Natural Killer (NK) cells were discovered ca 1975, as the first group of lymphoid cells that were neither T cells nor B cells. Since then, the dissection of the biology of NK cells has been growing exponentially with many seminal discoveries from the identification of MHC class I-specific inhibitory receptors to the discovery of receptor-ligand pairs involved in NK cell activation and to the manipulation of NK cells in cancer. In this research topic, we asked a group of thought leaders in NK cell biology to review recent advances in their origins and biology, and their roles in cancer, infection and inflammation. Together, these 25 articles provide a timely survey of NK cells as critical immunologic components of health and disease. They will hopefully prompt further dialogue and developments in basic and translational immunology. |
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2. |
Record Nr. |
UNINA9910300428603321 |
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Titolo |
Conflict and Complexity : Countering Terrorism, Insurgency, Ethnic and Regional Violence / / edited by Philip Vos Fellman, Yaneer Bar-Yam, Ali A. Minai |
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Pubbl/distr/stampa |
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New York, NY : , : Springer New York : , : Imprint : Springer, , 2015 |
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ISBN |
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Edizione |
[1st ed. 2015.] |
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Descrizione fisica |
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1 online resource (X, 292 p. 68 illus., 57 illus. in color.) |
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Collana |
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Understanding Complex Systems, , 1860-0832 |
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Disciplina |
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Soggetti |
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terrorism |
regional security |
ethnic conflict |
simulation |
Physics |
Social sciences |
Computational complexity |
Application software |
System safety |
Applications of Graph Theory and Complex Networks |
Methodology of the Social Sciences |
Complexity |
Computer Appl. in Social and Behavioral Sciences |
Security Science and Technology |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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"This volume is part of the NECSI Studies on Complexity collection."--Title page verso. |
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Nota di bibliografia |
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Includes bibliographical references. |
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Nota di contenuto |
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Preface -- Part I: The Theoretical Background -- Modeling Terrorist Networks: The Second Decade -- Complex Systems Studies and Terrorism -- The Psychology of Terrorism -- A Framework for Agent-based Social Simulations of Social Identity Dynamics -- DIME/PMESII Models -- Net-Centric Logistics: Complex systems science aims at moving targets -- Part II: Applications and Case Studies -- A Fractal Concept of War -- Disrupting Terrorist Networks, A Dynamic Fitness |
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Landscape Approach -- Comparison of approaches for adversary modeling decision support for counterterrorism -- The Landscape of Maritime Piracy and the Limits of Statistical Prediction -- Identities, Anonymity and Information Warfare -- Part II: Broader Horizons -- The Geography of Ethnic Violence -- Food Security and Political Instability: From Ethanol and Speculation to Riots and Revolutions -- South African Riots: Repercussion of the Global Food Crisis and US drought -- Conflict in Yemen: From Ethnic Fighting to Food Riots -- Complexity and the Limits of Revolution: What Will Happen to the Arab Spring?. |
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Sommario/riassunto |
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Complexity science affords a number of novel tools for examining terrorism, particularly network analysis and NK-Boolean fitness landscapes as well as other tools drawn from non-linear dynamical systems modeling. This book follows the methodologies of complex adaptive systems research in their application to addressing the problems of terrorism, specifically terrorist networks, their structure and various methods of mapping and interdicting them as well as exploring the complex landscape of network-centric and irregular warfare. A variety of new models and approaches are presented here, including Dynamic Network Analysis, DIME/PMESII models, percolation models and emergent models of insurgency. In addition, the analysis is informed by practical experience, with analytical and policy guidance from authors who have served within the U.S. Department of Defense, the British Ministry of Defence as well as those who have served in a civilian capacity as advisors on terrorism and counter-terrorism. |
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