1.

Record Nr.

UNINA9910300354503321

Autore

ten Donkelaar Hans J

Titolo

Clinical Neuroembryology : Development and Developmental Disorders of the Human Central Nervous System / / by Hans J. ten Donkelaar, Martin Lammens, Akira Hori

Pubbl/distr/stampa

Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2014

ISBN

3-642-54687-0

Edizione

[2nd ed. 2014.]

Descrizione fisica

1 online resource (675 p.)

Disciplina

599.935

599935

610

611.01816

Soggetti

Neurology 

Neurosciences

Human genetics

Neurology

Human Genetics

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references at the end of each chapters and index.

Nota di contenuto

Overview of the Development of the Human Brain and Spinal Cord -- Mechanisms of Development -- Causes of Congenital Malformations -- Neurulation and Neural tube Defects -- The Neural Crest and Craniofacial Malformations -- Development and Developmental Disorders of the Spinal Cord -- Development and Developmental Disorders of the Brain Stem -- Development and Developmental Disorders of the Human Cerebellum -- Development and Developmental Disorders of the Forebrain -- Development and Developmental Disorders of the Cerebral Cortex.

Sommario/riassunto

This book provides a comprehensive overview of the development of the human central nervous system (CNS) in the context of its many developmental disorders due to genetic, environmental, and hypoxic/ischemic causes. The introductory chapters give an overview of



the development of the human brain and the spinal cord, the mechanisms of development as obtained in experimental studies of various invertebrates and vertebrates, and  the causes of congenital malformations. In the main part, the developmental disorders of the human brain and the spinal cord are presented in a regional, more or less segmental way, starting with neurulation and neural tube defects, and ending with developmental disorders of the cerebral cortex. These are underlined by carefully chosen clinical case studies, including imaging data and, when available, postmortem verification of the developmental disorders involved. Numerous color photographs and illustrations complement the text. This second edition emphasizes the prenatal diagnosis by ultrasound, MRI, and DTI and implements new classifications of developmental disorders.