1.

Record Nr.

UNINA9910813359403321

Autore

Bar-Asher Mosheh

Titolo

Studies in classical Hebrew / / Moshe Bar-Asher ; edited by Aaron Koller

Pubbl/distr/stampa

Berlin, [Germany] : , : De Gruyter, , 2014

©2014

ISBN

3-11-048593-1

3-11-030039-7

3-11-030024-9

Descrizione fisica

1 online resource (492 p.)

Collana

Studia Judaica : Forschungen zur Wissenschaft des Judentums, , 0585-5306 ; ; Band 71

Disciplina

492.4/09

Soggetti

Hebrew language - History

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Frontmatter -- Preface -- Contents -- Introduction -- A. Biblical Hebrew -- 1 The Qal Passive Participle of Geminate Verbs in Biblical Hebrew -- 2. יריריה - וה׳ אהבז: The morphology and meaning of the word ידיד -- 3. The Bible Interpreting Itself -- 4. Gesenius' Thesaurus and Mishnaic Hebrew Studies -- 5 : איש יהודי היה בשושך הבידה When did יהודי Come to Denote 'Jew'? -- 6. Biblical Language in Mishnaic Texts -- 7. זצזמד אל יכבד לבד :Regarding One Sentence from the Letter to Pelatyahu -- 8. The verse שמע ישדאל ('Hear, O Israel') in Greek transcription on an ancient amulet -- B. Qumran Hebrew -- 9. A Few Remarks on Mishnaic Hebrew and Aramaic in Qumran Hebrew -- 10. On Several Linguistic Features of Qumran Hebrew -- 11. Qumran Hebrew Between Biblical and Mishnaic Hebrews: A Morphological Study -- 12. Mistaken Repetitions or Double Readings? -- 13. Two Issues in Qumran Hebrew: Synchronic and Diachronic Perspectives -- 14. Grammatical and Lexicographic Notes on a Qumran Fragment (4Q374 ii) -- 15. כיון הצלמים / כיניי הצלמים -- 16. The Patterns Pe'ila and Pi"ul in Qumran Hebrew -- C. Mishnaic Hebrew and Aramaic -- 17. Mishnaic Hebrew: An Introductory Survey -- 18. The Study of Mishnaic Hebrew Grammar Based on Written Sources: Achievements, Problems, and Tasks -- 19. The Different Traditions of Mishnaic Hebrew -- 20. The



System of binyanim in Mishnaic Hebrew (A Morphological Study) -- 21. The Formation of the Nif 'al III-yod Participle in Mishnaic Hebrew -- 22. Comments on the Morphology of Nouns in Mishnaic Hebrew: Nouns Attested and Unattested in Biblical Hebrew -- 23. Mishnaic Hebrew and Biblical Hebrew -- 24. On the Language of the Beit 'Amar Papyrus -- 25. From Oral Transmission to Written Transmission (Concerning the meaning of some orthographic forms in the manuscripts of the Mishnah and of Rabbinic Literature) -- Bibliography -- Indexes

Sommario/riassunto

Professor Moshe Bar-Asher, Professor Emeritus at the Hebrew University and long-time president of the Academy of the Hebrew Language, has published more than 200 articles and sixteen books and edited aboout 90 books and collections. The vast majority of his work has been accessible, however, only to specialists who read modern Hebrew or French. Bar-Asher's groundbreaking articles on the dialects of rabbinic literature are classics. In more recent years he has brought the same breadth and depth of grammatical knowledge, and philological acumen, to the study of older classical Hebrew texts, including literary and epigraphic texts.This volume presents studies of individual words and verses within the Bible, as well as broader thematic discussions of biblical language and its long reception-history, down through medieval scribes and modern lexicographers. Also represented are Bar-Asher's penetrating studies of Qumran texts and languages, which illuminate both the linguistic traditions reflected in these texts and the scribal culture from which they emerged. The third section contains studies of Mishnaic Hebrew. There are both sweeping surveys of the field and its accomplishments and challenges, and studies of specific phonological, morphological, syntactic and lexical features.



2.

Record Nr.

UNINA9910300313203321

Titolo

D-type Cyclins and Cancer / / edited by Philip W. Hinds, Nelson E. Brown

Pubbl/distr/stampa

Cham : , : Springer International Publishing : , : Imprint : Humana, , 2018

ISBN

3-319-64451-3

Edizione

[1st ed. 2018.]

Descrizione fisica

1 online resource (IX, 152 p. 29 illus., 25 illus. in color.)

Collana

Current Cancer Research, , 2199-2584

Disciplina

616.994071

Soggetti

Cancer - Research

Cell cycle

Molecular biology

Cancer Research

Cell Cycle Analysis

Molecular Medicine

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di bibliografia

Includes bibliographical references at the end of each chapters and index.

Nota di contenuto

The D-type Cyclins: A Historical Perspective -- Mammalian Development and Cancer – A Brief History of Mice Lacking D-type Cyclins or Cdk4/6 -- D-type Cyclins and Gene Transcription -- Splice Variants and Phosphorylated Isoforms of Cyclin D1 in Tumorigenesis -- Cyclin D1, Metabolism, and the Autophagy-Senescence Balance -- Shifting a Paradigm: Cyclin D Activates pRb by Mono-Phosphorylation.

Sommario/riassunto

This volume provides an integrated account of our current understanding of the functions of D-type cyclins during development and tumorigenesis, with special emphasis on the kinase-independent functions of these proteins. The volume will provide a thorough review of the latest discoveries on the new functions and interacting partners of mammalian cyclin Ds crucial to explain their oncogenic and differentiation properties in different cellular contexts. The volume begins with a historical perspective of how D-type cyclins were first discovered and eventually cloned from cancer tissues, followed by an account on the canonical functions of cyclin Ds during the G1-S



transition of the cell cycle. Several chapters will be devoted to review the functions of D-type cyclins as transcriptional regulators and the mechanisms through which these novel functions could impact the tumorigenic process. Also discussed is emerging evidence that points to a role of D-type cyclins, particularly cyclin D1, as a cytoplasmic regulator of various cellular functions. This property, in human cells at least, is traceable to certain splice isoforms with novel oncogenic implications. Finally, a chapter is devoted to recent efforts to revise the canonical view of the “retinoblastoma pathway” to incorporate new evidence that suggests that cyclin D1’s role in G1 is to singly-phosphorylate the retinoblastoma protein (pRb) for discrimination of target protein interactions. This work represents a significant departure from the view of cyclin D1 as a negative regulator of pRb and may have critical implications for understanding the function of antineoplastic agents that target the cyclin D1-associated kinases.