1.

Record Nr.

UNINA9910300231303321

Titolo

Rodent Transplant Medicine [[electronic resource] /] / edited by Weihua Gong

Pubbl/distr/stampa

Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2015

ISBN

94-017-9472-3

Edizione

[1st ed. 2015.]

Descrizione fisica

1 online resource (171 p.)

Disciplina

610

616.027

616079

617954

Soggetti

Surgical transplantation

Animal models in research

Immunology

Transplant Surgery

Animal Models

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Rodent Transplantation Medicine -- T Cell Costimulatory Molecules -- Age in Rodent Organ Transplantation -- Role of Gender in Animal Transplantation -- Role of Body-Weight/Functioning Mass of Graft in Rodent Transplantation  -- Illustration of Laboratory Facilities and Microsurgical Instruments -- Organ Preservation -- Rat Kidney Transplantation -- Rat Orthotopic Liver Transplantation -- Mouse Skin Transplantation -- Mouse Heterotopic Abdominal Heart Transplant Model -- Mouse Heterotopic Cervical Heart Transplant Model -- Mouse kidney Transplantation -- Mouse Liver Transplantation.

Sommario/riassunto

This book introduces transplantation in rodents as useful tools used in studying transplant immunobiology. Several solid organs (kidney, heart, liver) transplant models in rodents are described in this book. It can help surgical quality and save surgical time. The first part of the book provides a review of rodent transplant tolerance induction, the role of gender and body-weight in rodent transplantation, surgical instruments and organ preservation solutions. In the second part of the



book, various organ-transplantation techniques in rodents are discussed in individual chapters. This book presents uniform surgical procedures in mouse and rats, which produce comparable data, efficiently enhancing the translational research from bench to non-human primates and beyond. It will be of great value to transplant researchers, research fellows and clinicians in many surgical specialties. Editor Weihua Gong is an Associate Professor at the Department of Surgery, the 2nd Affiliated Hospital of Zhejiang University, China.