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Record Nr. |
UNINA9910300208803321 |
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Titolo |
Raynaud’s Phenomenon : A Guide to Pathogenesis and Treatment / / edited by Fredrick M. Wigley, Ariane L. Herrick, Nicholas A. Flavahan |
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Pubbl/distr/stampa |
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New York, NY : , : Springer New York : , : Imprint : Springer, , 2015 |
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ISBN |
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Edizione |
[1st ed. 2015.] |
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Descrizione fisica |
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1 online resource (400 p.) |
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Disciplina |
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Soggetti |
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Rheumatology |
Internal medicine |
Dermatology |
Internal Medicine |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references at the end of each chapters and index. |
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Nota di contenuto |
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Historical perspective of Raynaud's phenomenon -- definition, nomenclature and diagnostic criteria -- Epidemiology of Raynaud’s Phenomenon -- Thermoregulation: The Normal Structure and Function of the Cutaneous Vascular System -- Pathophysiological Regulation of the Cutaneous Vascular System in Raynaud’s Phenomenon -- Primary Raynaud’s Phenomenon -- Raynaud Phenomenon In The Pediatric Age.-Secondary Raynaud’s phenomenon -- Traumatic Vasospastic Disease -- Other Secondary Causes -- Raynaud’s Mimics -- Nailfold Capillaries.-Non-Invasive methods of assessing Raynaud’s phenomenon -- Angiography -- Autoantibodies in Raynaud’s Phenomenon -- Systemic Vasospasm -- Clinical Outcome Measures in Raynaud’s Phenomenon -- Design and reporting of randomised controlled trials for Raynaud’s phenomenon -- Non-drug Approaches to Treating Raynaud’s Phenomenon -- Drug Treatment of Raynaud’s Phenomenon -- Management of digital ischemia -- Surgical Management -- Practical Approaches to Treatment: Case Studies. |
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Sommario/riassunto |
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Raynaud’s Phenomenon: A Guide to Pathogenesis and Treatment comprehensively reviews the understanding of a disorder that continues to challenge primary care clinicians and specialists alike. In the last decade, there have been important advances not only in understanding the pathophysiology of Raynaud’s Phenomenon (RP), but also in developing diagnostic methods and effective drug and non-drug therapies. Thoroughly discussing the various manifestations of RP, including childhood RP, RP secondary to connective tissue disease, and a variety of other associated disorders that include vascular perturbation that mimics RP, this title provides a wealth of new information available on normal and abnormal thermoregulation and helps physicians identify the best therapeutic approaches to treating RP. The work offers differential diagnosis options, reviews potential causes -- such as autoimmune disease, industrial trauma, drugs, and metabolic causes -- and provides clear recommendations for therapy. Engaging readers with case vignettes and a plethora of visual aids, Raynaud’s Phenomenon: A Guide to Pathogenesis and Treatment is a state-of-the-art, authoritative reference and invaluable contribution to the literature that will be of interest to physicians, patients, and individuals dealing with these disease processes. |
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2. |
Record Nr. |
UNINA9910637714803321 |
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Autore |
Rapp Donald <1934-> |
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Titolo |
Human Missions to Mars : Enabling Technologies for Exploring the Red Planet / / by Donald Rapp |
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Pubbl/distr/stampa |
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Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 |
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ISBN |
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9783031207266 |
9783031207259 |
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Edizione |
[3rd ed. 2023.] |
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Descrizione fisica |
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1 online resource (650 pages) |
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Collana |
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Astronautical Engineering, , 2365-9602 |
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Disciplina |
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Soggetti |
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Outer space - Exploration |
Astronautics |
Aerospace engineering |
Solar system |
Automatic control |
Robotics |
Automation |
Space Exploration and Astronautics |
Aerospace Technology and Astronautics |
Space Physics |
Control, Robotics, Automation |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di contenuto |
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1. Why Explore Mars? -- 2. Planning Space Campaigns and Missions -- 3. 60+ Years of Humans to Mars Mission Planning -- 4. Getting There and Back -- 5. Critical Mars Mission Elements -- 6. In Situ Utilization of Indigenous Resources -- 7. Why the NASA approach will likely fail to send humans to Mars for many decades to come -- Appendix A. Solar Energy on the Moon -- Appendix B. Solar Energy on Mars -- Appendix C. Water on Mars -- Index. |
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Sommario/riassunto |
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A mission to send humans to explore the surface of Mars has been the ultimate goal of planetary exploration since the 1950s, when von Braun |
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conjectured a flotilla of 10 interplanetary vessels carrying a crew of at least 70 humans. Since then, more than 1,000 studies were carried out on human missions to Mars, but after 70 years of study, we remain in the early planning stages. The third edition of this book provides an annotated history of key Mars mission studies, with quantitative data wherever possible. Retained from the second edition, Donald Rapp looks at human missions to Mars from an engineering perspective. This includes analyzing the steps in the various proposed mission architectures, as well as the various vehicles and supporting technologies that are involved. In this connection, he discusses the status and potential of a wide range of technologies essential to a human mission to Mars, including life support, radiation, and low-gravity effects, getting there and back, in situ resource utilization, and mission safety. Detailed appendices describe availability of solar energy on the Moon and Mars, as well as the distribution of near-surface H2O. The third edition includes new information acquired from 2015 to 2022: · Significantly expanded discussion of Mars Ascent Vehicle · Discussion of the Moon-Mars connection · Review of a dozen additional Mars mission concepts · Expanded discussion of Ecological Life Support with emphasis on reliability issues · Expanded discussion of missions with nuclear propulsion · Extended review of new NASA Mars directions 2019-2022 · Expanded discussion of human factors and habitats · Expanded discussion of ISRU including results based on “MOXIE” on Mars · 33 new figures · 80 new references. |
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