1.

Record Nr.

UNINA9910300206203321

Titolo

Individualized Medicine : Ethical, Economical and Historical Perspectives / / edited by Tobias Fischer, Martin Langanke, Paul Marschall, Susanne Michl

Pubbl/distr/stampa

Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015

ISBN

3-319-11719-X

Edizione

[1st ed. 2015.]

Descrizione fisica

1 online resource (326 p.)

Collana

Advances in Predictive, Preventive and Personalised Medicine, , 2211-3509 ; ; 7

Disciplina

170

174.2

330

610

610.1

900

Soggetti

Medicine - Research

Biology - Research

Bioethics

Ethics

Business

Management science

History

Biomedical Research

Moral Philosophy and Applied Ethics

Business and Management

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Includes index.

Nota di contenuto

Preface -- Introduction -- Definition and concept of Individualized Medicine -- Perspectives of socio-cultural and historical studies -- Medical perspectives -- Concept-based ethical questions -- Applied research ethics -- Health economic assessment of Individualized Medicine -- Conclusions and recommendations -- Index.



Sommario/riassunto

In 2009 the University Medicine Greifswald launched the “Greifswald Approach to Individualized Medicine” (GANI_MED) to implement biomarker-based individualized diagnostic and therapeutic strategies in clinical settings. Individualized Medicine (IM) has led not only to controversies about its potentials, but also about its societal, ethical and health economic implications. This anthology focusses on these areas and includes – next to clinical examples illustrating how the integrated analysis of biomarkers leads to significant improvement of therapeutic outcomes for a subgroup of patients – chapters about the definition, history and epistemology of IM. Additionally there is a focus on conceptual philosophical questions as well as challenges for applied research ethics (informed consent process, the IT-based consent management and the handling of incidental findings). Finally it pays attention to health economic aspects.  The possibilities of IM to initiate a paradigm shift in the German health care provision are investigated. Furthermore, it is asked whether the G-DRG system is ready for the implementation of such approaches into clinical routine.