|
|
|
|
|
|
|
|
1. |
Record Nr. |
UNINA9910300133003321 |
|
|
Autore |
Efendiev Messoud |
|
|
Titolo |
Mathematical Modeling of Mitochondrial Swelling / / by Messoud Efendiev |
|
|
|
|
|
|
|
Pubbl/distr/stampa |
|
|
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 |
|
|
|
|
|
|
|
|
|
ISBN |
|
|
|
|
|
|
Edizione |
[1st ed. 2018.] |
|
|
|
|
|
Descrizione fisica |
|
1 online resource (230 pages) |
|
|
|
|
|
|
Disciplina |
|
|
|
|
|
|
Soggetti |
|
Biomathematics |
Dynamics |
Ergodic theory |
Cell physiology |
Physiological, Cellular and Medical Topics |
Dynamical Systems and Ergodic Theory |
Cell Physiology |
|
|
|
|
|
|
|
|
Lingua di pubblicazione |
|
|
|
|
|
|
Formato |
Materiale a stampa |
|
|
|
|
|
Livello bibliografico |
Monografia |
|
|
|
|
|
Nota di contenuto |
|
Functional Spaces -- Biological Background -- Model Description -- Mathematical Analysis of Vitro Models -- The Swelling of Mitochondria: In Vivo -- The Swelling of Mitochondria: Degenerate Diffusion -- The Spatial Evolution of Mitochondria: PDE-PDE Systems. |
|
|
|
|
|
|
|
|
Sommario/riassunto |
|
The mathematical models considered in this book can help to understand the swelling of mitochondria. For the first time, it presents new mathematical models of mitochondrial swelling that take into account, in particular, spatial effects. The results presented here could make it possible to predict properties of the underlying biological mechanisms. Taking into account that mitochondria could move within a cell, lead to a PDE-PDE model. The book discusses the well-posedness and long-term dynamics of solutions, depending on boundary conditions reflecting the in vitro and in vivo cases. These analytical and numerical results have inspired colleagues from the Institute of Pharmacology and Toxicology of the Helmholtz Center Munich to design new experiments justifying the theoretical and |
|
|
|
|