Molecular Testing in Cancer / / edited by George M. Yousef, Serge Jothy

• Record Nr.: UNINA9910300077103321
• Pubbl/distr/stampa: New York, NY : , : Springer New York : , : Imprint : Springer, , 2014
• ISBN: 1-4899-8050-4
• Edizione: [1st ed. 2014.]
• Descrizione fisica: 1 online resource (437 p.)
• Disciplina: 610; 610724; 614.5999; 616.07
• Soggetti: Pathology; Hematology; Laboratory medicine; Cancer research; Laboratory Medicine; Cancer Research
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Transitioning Diagnostic Molecular Pathology to the Genomic Era: Cancer Somatic Mutation Panel Testing -- Conventional and Molecular Cytogenetics in Cancer -- Comparative Genomic Hybridization and Array based CGH in Cancer -- Polymerase Chain Reaction -- Single Nucleotide Polymorphisms (SNPs) -- Clinical Application of DNA Sequencing: Sanger and Next-Generation Platforms -- Microarray-based Investigations in Cancer -- Proteomics in Cancer Diagnostics -- Circulating Tumor Cells: A Non-Invasive Liquid Biopsy in Cancer -- Molecular Testing in Hematological Malignancies -- Molecular Testing in Breast Cancer -- Molecular Pathology of Gastrointestinal Tumors -- Molecular Testing in Pulmonary Tumors -- Molecular testing in Gynecological Malignancies -- Molecular Testing in Central Nervous System tumors -- Molecular Testing in Adult Kidney Tumors -- Molecular Testing in Prostate Cancer -- Molecular Testing in Urothelial Tumors -- Molecular Testing in Thyroid Cancer -- Molecular ; Testing of Head and Neck Tumors -- Molecular Testing in Bone and Soft Tissue Tumors -- Molecular testing in Cutaneous Melanoma -- Molecular Testing in Pediatric Tumors -- Pharmacogenomics in Molecular Oncology -- Quality Assurance in Molecular Testing of Cancer.
• Sommario/riassunto: Molecular Testing in Cancer provides a state of the art review of clinically relevant molecular pathology in cancer. The book provides a brief, easy to read review of commonly employed diagnostic molecular techniques including recently developed "next generation" analytic tools, and offers a system-based run-through of the utility of molecular testing in individual cancer types, as well as reviewing current markers in cancer diagnosis, prognosis, and management. The volume also provides a prospective for the future which includes recently characterized and emerging biomarkers. Written by experts in the field, Molecular Testing in Cancer serves as a useful and comprehensive resource for pathologists, hematologists, laboratory technicians and molecular scientists.