1.

Record Nr.

UNINA9910299667503321

Autore

Yannas Ioannis V

Titolo

Tissue and Organ Regeneration in Adults [[electronic resource] ] : Extension of the Paradigm to Several Organs / / by Ioannis V. Yannas

Pubbl/distr/stampa

New York, NY : , : Springer New York : , : Imprint : Springer, , 2015

ISBN

1-4939-1865-6

Edizione

[2nd ed. 2015.]

Descrizione fisica

1 online resource (XXIII, 332 p. 61 illus., 21 illus. in color.)

Disciplina

571.889

Soggetti

Biomedical engineering

Biomedical materials

Dermatology

Biotechnology

Biomedical Engineering and Bioengineering

Biomaterials

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Bibliographic Level Mode of Issuance: Monograph

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

The Irreversibility of Organ Injury -- Nonregenerative Tissues -- Experimental Methods I. The Anatomically Well-Defined Wound -- Experimental Methods II. The Defect Closure Rule -- Regeneration of Skin -- Regeneration of a Peripheral Nerve -- Minimum Reactants Required for Synthesis of Skin and Peripheral Nerves; Extension to Tissues of Other  Organs -- An Antagonistic Relation Between Wound Contraction and Regeneration -- Molecular biology of contraction blockade by active scaffolds -- The Scaffold Regeneration Paradigm and its Consequences.

Sommario/riassunto

This textbook describes the basic principles of induced organ regeneration in skin and peripheral nerves and extends the original successful paradigm to other organs. A set of trans-organ rules is established and its use in regeneration of several organs is illustrated from the works of several independent investigators who worked with a variety of organs, such as the lung, the bladder, and the Achilles tendon, using collagen-based scaffolds somewhat similar to the original one. These critical medical treatments fill the clinical need that is not met by organ transplantation. New to this second edition: New



information extending the paradigm of tissue regeneration from organ regeneration in skin and peripheral nerves to other organs Guidelines, known as trans-organ rules, are described for the first time for extending this unique medical treatment to organs of several medical specialties The work serves as a comprehensive text and reference for students and practitioners of tissue engineering  .