Clinical psychology and psychotherapy as a science : an iconoclastic perspective / / Luciano L'Abate

• Record Nr.: UNINA9910437967103321
• Autore: L'Abate Luciano <1928->
• Pubbl/distr/stampa: New York, : Springer, c2013
• ISBN: 9781461444510; 1461444519; 1461444503; 1-283-62414-1; 9786613936592
• Edizione: [1st ed. 2013.]
• Descrizione fisica: 1 online resource (377 p.)
• Disciplina: 150; 616.89; 616.89/14; 616.8914
• Soggetti: Clinical psychology - Philosophy; Psychotherapy - Philosophy
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references (p. 336-356) and index.
• Nota di contenuto: Historical Introduction to Clinical Psychology and Psychotherapy -- Toward a Science of Clinical Psychology and Psychotherapy: Theory and Practice -- The Cults of Psychotherapy -- Beyond Reliability and Validity: Toward Specificity in Clinical Psychology and Psychotherapy -- Stepped Care Research in Clinical Psychology and Psychotherapy -- Concreteness: Seven Psychological Orphans in Search of a Theory-Toward a Neo-behaviorist View -- Epilogue and Conclusions: Toward a Hierarchical Personnel Structure in Clinical Psychology and Psychotherapy.
• Sommario/riassunto: Clinical Psychology and Psychotherapy as a ScienceAn Iconoclastic Perspective Luciano L’Abate Since its inception, psychology has worked to establish itself as a legitimate scientific endeavor. Countless research studies have tested numerous theories and therapies, determining what works and what doesn’t, and building a vast store of ; empirical knowledge. Now a startling and provocative new volume suggests that the problem withthe evidence base is that it is not scientific enough—and that the major modes of therapy are on their way out. In Clinical Psychology and Psychotherapy as a Science, Luciano L’Abate expands on his previously controversial ideas, taking to task the one-to-one, face-to-face, talking-cure paradigm that has been entrenched for over a century. Citing the rise of self-help manuals, workbooks, written interactive practice exercises, and websites, he predicts the continued ascendance of writing in communication and healing, and details the contributions of technology in creating less-invasive homework-based interventions. These are presented as an efficient, cost-effective, and replicable alternative to traditional forms of therapy, and the author explains how their therapeutic gains can be achieved without sacrificing the therapeutic relationship. Included in the coverage are: • The case for distance writing and computer conferences. • Beyond reliability and validity: the quest for specificity. • Stepped care research in clinical psychology and psychotherapy. • Concreteness, or seven orphaned concepts in search of a theory. • Toward a hierarchical personnel structure in clinical psychology and psychotherapy. • Plus an appendix of supplemental workbooks for adults, children, adolescents, and families. As with the author’s other works, Clinical Psychology and Psychotherapy as a Science will spark debate and interest among researchers and clinical psychologists and psychotherapists.

The Hsp60 Chaperonin / / by Peter Bross

• Record Nr.: UNINA9910298447903321
• Autore: Bross Peter
• Pubbl/distr/stampa: Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015
• ISBN: 3-319-26088-X
• Edizione: [1st ed. 2015.]
• Descrizione fisica: 1 online resource (90 p.)
• Collana: Protein Folding and Structure, , 2199-3157
• Disciplina: 572.645
• Soggetti: Proteins; Bioorganic chemistry; Molecular biology; Protein Science; Bioorganic Chemistry; Molecular Medicine; Xaperones moleculars; Llibres electrònics
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references.
• Nota di contenuto: Introduction -- Historical sketch of the discovery and recognition of the function of chaperonins -- Molecular structure of chaperonins -- Folding by enclosure in the chaperonin cavity -- Evolutionary origins and family relations -- Chaperoning mechanisms: folding helpers, folding protectors or misfolding blockers? -- Sequence variations in proteins affecting chaperonin dependence -- Genetic organization of type I chaperonin genes -- Regulation of type I chaperonin gene expression -- Subcellular localization -- Posttranslational modifications -- Variations in Hsp60 and Hsp10 in humans -- Type I chaperonins are essential for cell viability and mutations cause deficiency phenotypes -- Human diseases caused by genetic mutations in the Hsp60/Hsp10 system -- Molecular investigations of disease mechanisms -- Molecular investigations of disease mechanisms -- Outlook.
• Sommario/riassunto: In this unique overview of the Hsp60 chaperonin, Peter Bross addresses molecular biologists, medical research scientists and individuals ; interested in molecular or general biology. First, Bross discusses the basics of the Hsp60 chaperonin in terms of its structure and the molecular mechanisms determining its function. Second, the author highlights the multiple roles of Hsp60 for cellular systems and regulatory pathways, especially in connection with neurodegenerative diseases caused by Hsp60 deficiency. Finally, the author highlights controversial observations suggesting additional, non-standard functions of Hsp60 in and outside mitochondria as well as possible gaps in our understanding of the chaperonin. This volume serves as a snapshot suitable for experienced researcher working in fields related to molecular chaperones yet still accessible to researchers entering the field.