1.

Record Nr.

UNINA9910298432403321

Titolo

Activation of Viruses by Host Proteases / / edited by Eva Böttcher-Friebertshäuser, Wolfgang Garten, Hans Dieter Klenk

Pubbl/distr/stampa

Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018

ISBN

3-319-75474-2

Edizione

[1st ed. 2018.]

Descrizione fisica

1 online resource (337 pages)

Disciplina

576.64

Soggetti

Virology

Enzymology

Proteins 

Protein-Ligand Interactions

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di contenuto

Introduction -- Viruses -- Influenzaviruses -- Paramyxo-, Hendra-, Nipahviruses -- Coronaviruses -- Flaviviruses -- Arenaviruses -- Filoviruses -- Proteases -- Proproteinconvertases -- Serinproteases -- Transmembrane serinproteases -- Cathepsins -- Protease inhibitors.

Sommario/riassunto

This book will give an overview on viruses undergoing proteolytic activation through host proteases. The chapters will be organized in three themed parts, the first part describing respective viruses and their characteristics in detail. In the second part the molecular and cellular biology of the proteases involved as well as their physiological functions will be further explored. The third part will contain a chapter on protease inhibitors that are promising tools for antiviral therapy. This book will engage scholars in virology and medical microbiology as well as researchers with an interest in enzymology and protein structure and function relationship.