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1. |
Record Nr. |
UNINA9910789894603321 |
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Autore |
Anscombe G. E. M (Gertrude Elizabeth Margaret) |
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Titolo |
From Plato to Wittgenstein [[electronic resource] ] : essays by G. E. M. Anscombe / / edited by Mary Geach and Luke Gormally |
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Pubbl/distr/stampa |
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[Luton, Bedfordshire, England], : Andrews U.K., 2011 |
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ISBN |
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1-84540-236-7 |
1-283-44522-0 |
9786613445223 |
1-84540-245-6 |
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Descrizione fisica |
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1 online resource (294 p.) |
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Collana |
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St. Andrews studies in philosophy and public affairs ; ; v. 18 |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Originally published in the U.K. by Imprint Academic. |
Originally published in the U.S.A. by Imprint Academic. |
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Nota di bibliografia |
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Includes bibliographical references. |
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Nota di contenuto |
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pt. 1. Ancient, medieval & modern -- pt. 2. Recent and contemporary. |
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Sommario/riassunto |
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In 2005 St Andrews Studies published a volume of essays by Anscombe entitled Human Life, Action and Ethics, followed in 2008 by a second with the title Faith in a Hard Ground. Both books were highly praised. This third volume brings essays on the thought of historical philosophers in which Anscombe engages directly with their ideas and arguments. Many are published here for the first time and the collection provides further testimony to Anscombe's insight and intellectual imagination. |
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2. |
Record Nr. |
UNINA9910298349303321 |
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Titolo |
Tumor-Induced Immune Suppression : Mechanisms and Therapeutic Reversal / / edited by Dmitry I. Gabrilovich, Arthur Andrew Hurwitz |
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Pubbl/distr/stampa |
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New York, NY : , : Springer New York : , : Imprint : Springer, , 2014 |
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ISBN |
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Edizione |
[2nd ed. 2014.] |
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Descrizione fisica |
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1 online resource (471 p.) |
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Disciplina |
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Soggetti |
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Cancer - Research |
Immunology |
Medical microbiology |
Cytology |
Human genetics |
Developmental biology |
Cancer Research |
Medical Microbiology |
Cell Biology |
Human Genetics |
Developmental Biology |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references at the end of each chapters and index. |
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Nota di contenuto |
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Preface.- Regulatory T Cells and Cancer -- Th17 cells in cancer -- Mast cells and immune response in cancer -- Myeloid-Derived Suppressor Cells in Tumor-Induced T-Cell Suppression and Tolerance -- Immunobiology of Dendritic Cells in Cancer -- Macrophages and Tumor Development -- Angiogenesis and Immune Suppression in Cancer -- Tim-3 Regulation of Cancer Immunity.- Transcriptional Regulation of Dendritic Cells in The Tumor Microenvironment -- S100A9, Inflammation, and Regulation of Immune Suppression in |
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Cancer -- IDO in Inflammatory Programming and Immune Suppression in Cancer -- Defining the Fate and Function of Effector T cells through Galectin-1 – Galectin-1 Ligand Binding Interactions: Implications in Tumor Immunity -- Arginine Metabolism, a Major Pathway for the Suppressive Function of Myeloid-derived Suppressor Cells.- The Hypoxia-Adenosinergic Immunosuppression and Redirection of Immune Response in Tumor Microenvironment -- Molecular Pathways in Antigen Presenting Cells Involved in the Induction of Antigen-Specific T-Cell Tolerance -- Overcoming Immune Suppression: Therapeutic Strategies Targeting T-Cell Function in Cancer -- Index. |
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Sommario/riassunto |
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Tumor-Induced Immune Suppression - Prospects and Progress in Mechanisms and Therapeutic Reversal presents a comprehensive overview of large number of different mechanisms of immune dysfunction in cancer and therapeutic approaches to their correction. This includes the number of novel mechanisms that has never before been discussed in previous monographs. The last decades were characterized by substantial progress in the understanding of the role of the immune system in tumor progression. Researchers have learned how to manipulate the immune system to generate tumor specific immune response, which raises high expectations for immunotherapy to provide breakthroughs in cancer treatment. It is increasingly clear that tumor-induced abnormalities in the immune system not only hampers natural tumor immune surveillance, but also limits the effect of cancer immunotherapy. Therefore, it is critically important to understand the mechanisms of tumor-induced immune suppression to make any progress in the field and this monograph provides these important insights. |
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