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Record Nr. |
UNINA9910298345403321 |
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Titolo |
Neurobiological Studies of Addiction in Chronic Pain States / / edited by Carolyn A. Fairbanks, Thomas J. Martin, Ph.D |
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Pubbl/distr/stampa |
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New York, NY : , : Springer New York : , : Imprint : Springer, , 2014 |
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ISBN |
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Edizione |
[1st ed. 2014.] |
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Descrizione fisica |
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1 online resource (137 p.) |
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Collana |
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Contemporary Clinical Neuroscience, , 2627-535X ; ; 17 |
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Disciplina |
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610 |
612.8 |
616.027 |
616.0472 |
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Soggetti |
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Neurosciences |
Pain medicine |
Animal models in research |
Pain Medicine |
Animal Models |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references at the end of each chapters and index. |
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Nota di contenuto |
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Opioid and Non-Opioid Drug Responding Under States of Chronic Pain: A Timeline Spanning 1980 to Present Day -- Opioid Self-Administration in the Presence of Chronic Pain: Analgesia or Addiction -- The Influence of Pain on Reward Processing: Current Literature and Prospects -- Chronic Pain Stimuli Downregulate Mesolimbic Dopaminergic Transmission: Possible Mechanism of the Suppression of Opioid Reward -- Drug Addiction and Chronic Pain: A Review of Animal Models -- Biopharmaceutical Considerations of Opioid Analgesics in Models of Self-Administration: Review and Summary -- Prenatal Exposure to Opioids -- Opioids in an Evidence-Based World. |
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Sommario/riassunto |
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Using rodent models, the contributors explore the basic neurobiology of the relationship among chronic pain, opioid pharmacology, and addiction. Combining various pain models with opioid self-administration and central administration pharmacotherapies allows researchers to answer important questions about: 1. The efficacy of |
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