1.

Record Nr.

UNINA9910298342503321

Autore

Aravalli Rajagopal N

Titolo

Hepatocellular Carcinoma : Cellular and Molecular Mechanisms and Novel Therapeutic Strategies / / by Rajagopal N. Aravalli, Clifford J. Steer

Pubbl/distr/stampa

Cham : , : Springer International Publishing : , : Imprint : Springer, , 2014

ISBN

3-319-09414-9

Edizione

[1st ed. 2014.]

Descrizione fisica

1 online resource (74 p.)

Collana

SpringerBriefs in Cancer Research, , 2194-1173

Disciplina

610

614.5999

615.19

616994

Soggetti

Cancer research

Oncology  

Pharmaceutical technology

Cancer Research

Oncology

Pharmaceutical Sciences/Technology

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Introduction -- Etiology -- Current diagnosis and treatment options for HCC -- Pathophysiology of HCC -- Molecular mechanisms of HCC -- Animal models of liver cancer -- Novel therapeutic strategies to combat HCC -- Conclusions.

Sommario/riassunto

This book provides up-to-date information on the development and progression of hepatocellular carcinoma (HCC) with a review of the cellular and molecular mechanisms involved in the disease process. Recent research in HCC has led to significant progress in our understanding of the cellular processes and molecular mechanisms that occur during multi-stage events that lead to hepatocarcinogenesis. The emergence of micro RNAs and molecular targeted therapies have added a new dimension in our efforts to combat this deadly disease, Chapters include discussion and evaluation of current intervention strategies and



therapeutic options and a focus on the novel approaches that are being pursued, such as micro-RNA based therapies and personalized medicine to treat liver cancer. This book will be of interest to basic and clinical researchers, as well as to drug developers.