1.

Record Nr.

UNINA9910298317003321

Autore

Dickhaus Thorsten

Titolo

Simultaneous Statistical Inference : With Applications in the Life Sciences / / by Thorsten Dickhaus

Pubbl/distr/stampa

Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2014

ISBN

3-642-45182-9

Edizione

[1st ed. 2014.]

Descrizione fisica

1 online resource (182 p.)

Disciplina

006.312

519.5

570

570.15195

Soggetti

Biometry

Statistics

Biomathematics

Data mining

Biomedical engineering

Biostatistics

Statistical Theory and Methods

Mathematical and Computational Biology

Data Mining and Knowledge Discovery

Biomedical Engineering and Bioengineering

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references at the end of each chapters and index.

Nota di contenuto

The problem of simultaneous inference -- Part I General Theory -- Some theory of p-values -- Classes of multiple test procedures -- Simultaneous test procedures -- Stepwise rejective multiple tests -- Multiple testing and binary classification -- Multiple testing and model selection -- Software solutions for multiple hypotheses testing -- Part II From Genotype to Phenotype -- Genetic association studies -- Gene expression analyses -- Functional magnetic resonance imaging -- Part III Further Applications in the Life Sciences -- Further life science



applications.

Sommario/riassunto

This monograph will provide an in-depth mathematical treatment of modern multiple test procedures controlling the false discovery rate (FDR) and related error measures, particularly addressing applications to fields such as genetics, proteomics, neuroscience and general biology. The book will also include a detailed description how to implement these methods in practice. Moreover, new developments focusing on non-standard assumptions are also included, especially multiple tests for discrete data. The book primarily addresses researchers and practitioners but will also be beneficial for graduate students.