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1. |
Record Nr. |
UNINA990003090100403321 |
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Autore |
Bouthoul, Gaston <1896-1980> |
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Titolo |
Le guerre : Elementi di polemologia : Metodi, teorie e opinioni sulla guerra. Morfologia. Elementi tecnici, demografici, economici, psicologici. Periodicità delle guerre / Gaston Bouthoul |
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Pubbl/distr/stampa |
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Milano : Longanesi, \c\\1961 |
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Descrizione fisica |
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Collana |
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Disciplina |
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Locazione |
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Collocazione |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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2. |
Record Nr. |
UNINA9910300183303321 |
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Titolo |
Frontiers in Gynecological Endocrinology : Volume 2: From Basic Science to Clinical Application / / edited by Bart C.J.M. Fauser, Andrea R. Genazzani |
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Pubbl/distr/stampa |
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Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 |
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ISBN |
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Edizione |
[1st ed. 2015.] |
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Descrizione fisica |
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1 online resource (190 p.) |
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Collana |
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Disciplina |
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Soggetti |
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Gynecology |
Endocrinology |
Reproductive health |
Reproductive Medicine |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Adolescent Gynecology: Disorders of the menstrual cycle during adolescence -- From life-style to insulin sensitizers for PCOS -- Polycystic ovary syndrome: from contraception to Hormone Replacement Therapy -- Management of adolescent hyperandrogenism -- Prevention of adolescent pregnancies -- Transsexualism: endocrine aspects -- Hormonal Contraception: How to find the right the contraceptive method for the right woman -- Hormonal Contraceptives: Progestogen and Thrombotic Risk -- Heavy Menstrual Bleeding, Fibroids, Adenomyosis and Endometriosis: Heavy menstrual bleeding – the daily challenge for the gynecologist -- Fibroids and adenomyosis, current treatment options -- Effects on sexual function of medical and surgical therapy for endometriosis -- Assisted Reproduction: the Endocrine Impact: In patients with only one or two oocytes, is it better IVF-ET or ICSI? -- Supplementation with DHEAS in poor responder patients -- Premature ovarian failure: how to solve fertility -- Metabolic |
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Syndrome: Endocrine and Metabolic Disorders in Aging Women -- Obesity and Metabolic Syndrome: impact and relationship with menopausal transition -- Menopause: Cardiovascular prevention at the menopausal transition: role of hormonal therapies -- Menopause and HRT: doubts and certainties -- Breast Cancer: Androgen receptor and breast cancer -- Breast cancer: preservation of fertility and pregnancy after cancer -- Low Malignant ovarian tumors. |
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Sommario/riassunto |
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This volume offers an up-to-date overview on the major areas of gynecological endocrinology, presenting the latest advances in adolescent gynecological endocrinology, assisted reproduction, menstrual-related disorders, sexuality and transsexualism, polycystic ovary syndrome, myometrial pathology and adenomyosis, obesity and metabolic syndrome, hormonal contraception, premature ovarian failure and menopause. In each chapter the recent advances deriving from basic science and clinical investigations are related to the practical management of the condition under consideration, taking into account the need for individualized therapies. The book is published within the ISGE Book Series, a joint venture between the International Society of Gynecological Endocrinology and Springer and is based on the 2014 International School of Gynecological and Reproductive Endocrinology Winter Course. It will be an important tool for obstetricians and gynecologists, endocrinologists and experts in women’s health as well as interested GPs. |
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3. |
Record Nr. |
UNINA9910298302803321 |
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Titolo |
Calcium Signaling In Airway Smooth Muscle Cells / / edited by Yong-Xiao Wang |
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Pubbl/distr/stampa |
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Cham : , : Springer International Publishing : , : Imprint : Springer, , 2014 |
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ISBN |
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Edizione |
[1st ed. 2014.] |
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Descrizione fisica |
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1 online resource (470 p.) |
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Disciplina |
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Soggetti |
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Cytology |
Biochemistry |
Human physiology |
Cell Biology |
Biochemistry, general |
Human Physiology |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Ryanodine and Inositol Trisphosphate Receptors/Ca2+ Release Channels in Airway Smooth Muscle Cells -- Kv7 (KCNQ) Potassium Channels and L-type Calcium Channels in the Regulation of Airway Diameter -- Transient Receptor Potential and Orai Channels in Airway Smooth Muscle Cells -- Large-conductance calcium-activated potassium channels -- Calcium-activated Chloride Channels -- Local Calcium Signaling in Airway Smooth Muscle Cells -- Regulation of Airway Smooth Muscle Contraction by Ca2+ Signaling: Physiology Revealed by Microscopy Studies of Lung Slices -- Temporal Aspects of Ca2+ Signaling in Airway Myocytes -- Mechanisms Underlying Ca2+ Store Refilling in Airway Smooth Muscle -- Novel Mechanisms in Ca2+-homeostasis and Internal Store Refilling of Airway Smooth Muscle -- The Role of Mitochondria in Calcium Regulation in Airway Smooth Muscle -- Role of Caveolae in the Airway -- CD38 – Cyclic ADP-ribose- |
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mediated Calcium Signaling in Airway Myocytes -- The Pathways and Signaling Cross-talk with Oxidant in Calcium Influx in Airway Smooth Muscle Cells -- Role of RhoA/Rho-kinase and Calcium Sensitivity in Airway Smooth Muscle Functions -- Role of Integrins in the Regulation of Calcium Signaling -- Sex Steroid Signaling in the Airway -- Regulation of Contractility in Immature Airway Smooth Muscle -- Mathematical Modeling of Calcium Dynamics in Airway Smooth Muscle Cells -- Effects of Inflammatory Cytokines on Ca2+ Homeostasis in Airway Smooth Muscle Cells -- Ca2+ Signaling and P2 Receptors in Airway Smooth Muscle -- Calcium Signaling in Airway Smooth Muscle Remodeling -- Regulation of Intracellular Calcium by Bitter Taste Receptors on Airway Smooth Muscle -- Modulation of Airway Smooth Muscle Contractile Function by TNFa and IL-13 and Airway Hyper-responsiveness in Asthma -- Airway Smooth Muscle Malfunction in COPD. |
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Sommario/riassunto |
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Calcium signaling plays an important role in cellular responses in almost all types of cells including airway smooth muscle cells. This universal signaling may result from extracellular calcium influx and/or intracellular calcium release, which are precisely controlled and regulated by ion channels, exchangers and/or transporters on the plasmalemmal or sarcoplasmic reticulum membrane. First, several chapters detail calcium release channels (ryanodine receptors and inositol trisphosphate receptors), voltage-dependent potassium channels, transient receptor potential channels, Orai channels, calcium-activated potassium channels, and calcium-activated chloride channels. Discussion of well-characterized sodium-calcium exchangers, voltage-dependent calcium channels, and calcium pumps are described in depth over many chapters. Ca2+ signaling can be expressed in Ca2+ sparks, waves, oscillations, and global changes in intracellular Ca2+ concentration. Calcium in subcellular compartments (cytosol, sarcoplasmic reticulum, mitochondria, and caveolae) also exhibit dynamic crosstalk. Many molecules including FK506 binding proteins, cyclic adenosine diphosphate ribose, reactive oxygen species, RhoA kinases, caveolin and integrins can modify and induce spatial, temporal and compartmental variations of calcium signaling. In addition, calcium signaling can exhibit sex hormone- and age-dependent changes. A number of chapters are dedicated to covering these diverse formats, spatiotemporal characteristics, multifaceted network and mathematical modeling of Ca2+ signaling. Neurotransmitters, hormones, growth factors, inflammatory cytokines, and other stimuli may lead to multiple cellular responses by inducing Ca2+ signaling in airway smooth muscle cells. Increasing evidence suggests that Ca2+ pumps and canonical transient receptor potential channels are essential for airway smooth muscle remodeling. Accordingly, several chapters summarize recent advances in the studies of the key role of calcium signaling in physiological cellular responses as well as the development of asthma, chronic obstructive pulmonary disease and other respiratory disorders. About the Editor Dr. Yong-Xiao Wang is a Professor at Albany Medical College and has been working on cell calcium, ion channels, and neurotransmitter receptors in airway smooth muscle cells for many years. He has been one of the leading scientists in the field, evident by his excellent record of research publications, funding and service activities. |
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