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1. |
Record Nr. |
UNINA9910296438903321 |
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Autore |
Aubry Bruno |
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Titolo |
Journées archéologiques de Haute-Normandie. Rouen, 11-13 mai 2012 / / Luc Liogier |
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Pubbl/distr/stampa |
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Mont-Saint-Aignan, : Presses universitaires de Rouen et du Havre, 2018 |
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ISBN |
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Descrizione fisica |
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1 online resource (262 p.) |
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Altri autori (Persone) |
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BahainJean-Jacques |
BailliotMagali |
BertaudièreSandrine |
CalderoniPaola |
CamusetJean-Louis |
CliquetDominique |
CormierSébastien |
DartoisVincent |
DeshayesGilles |
DuboisStéphane |
DumondelleGilles |
FarautAlain |
FarautMonique |
FerreiraFilipe |
HartzCécile |
JégoLaurence |
LautridouJean-Pierre |
Le BorgneJean-Noël |
Le BorgneVéronique |
Le MahoJacques |
Limondin-LozouetNicole |
LiogierLuc |
MantelÉtienne |
MarcignyCyril |
MartinRégis |
MazetSylvain |
MichelJean-Marie |
MouchardJimmy |
NewmanCharlie |
RavonÉlisabeth |
Remy-WattéMonique |
RenardCaroline |
ThomannAminte |
VincentJean-Baptiste |
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VoinchetPierre |
WattéJean-Pierre |
WechPierre |
WeillPierre-Manuel |
LequoyMarie-Clotilde |
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Soggetti |
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Archaeology |
Haute-Normandie |
fouille |
site archéologique |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Sommario/riassunto |
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Comme chaque année, les Journées archéologiques de Haute-Normandie permettent la restitution au public des travaux et des opérations de terrain récents. Cinq thèmes ont été retenus en 2012 : la Seine, axe de circulation et pôle d'attraction pour les sociétés humaines depuis la préhistoire ; voir et percevoir, sujet qui a l'avantage de mettre en perspective l'histoire de la discipline ; le quotidien, abordé par l'habitat et par les productions spécifiques comme la faïence ; le monumental, dont le grand sanctuaire et le théâtre antiques du Vieil-Évreux, ainsi que le théâtre de Lillebonne sont emblématiques ; le spirituel, représenté notamment par les abbayes de Mortemer et Saint-Taurin d'Évreux, qui viennent rappeler que l'archéologie ne se limite pas aux traces enfouies mais concerne aussi les vestiges en élévation par l'étude du bâti. |
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2. |
Record Nr. |
UNINA9910136800603321 |
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Autore |
Atsuhiko Ichimura |
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Titolo |
Obesity and Diabetes: Energy Regulation by Free Fatty Acid Receptors |
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Pubbl/distr/stampa |
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Descrizione fisica |
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1 electronic resource (45 p.) |
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Collana |
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Frontiers Research Topics |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Sommario/riassunto |
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Food intake regulates energy balance and its dysregulation leads to metabolic disorder, such as obesity and diabetes. During feeding, free fatty acids (FFAs) are not only essential nutrients but also act as signaling molecules in various cellular processes. Recently, several orphan G protein-coupled receptors (GPCRs) that act as FFA receptors (FFARs) have been identified; GPR40/FFAR1, GPR119, and GPR120 are activated by medium- and long-chain FFAs. GPR84 is activated by medium-chain FFAs. GPR41/FFAR3 and GPR43/FFAR2 are activated by short-chain FFAs. These FFARs have come to be regarded as new drug targets for metabolic disorder such as obesity and type 2 diabetes, because a number of pharmacological and physiological studies have shown that these receptors are primarily involved in the energy metabolism in various tissues; insulin secretion, gastrointestinal hormone secretion, adipokine secretion, regulation of inflammation, regulation of autonomic nervous system, relation to gut microbiota, and so on. This Research Topic provides a comprehensive overview of the energy regulation by free fatty acid receptors and a new prospect for treatment of metabolic disorder such as obesity and type 2 diabetes. |
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