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Record Nr. |
UNINA9910557702003321 |
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Autore |
Cuenda Ana |
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Titolo |
P38 Signaling Pathway |
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Pubbl/distr/stampa |
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Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
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Descrizione fisica |
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1 online resource (194 p.) |
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Soggetti |
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Research and information: general |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Sommario/riassunto |
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p38 Mitogen activated protein kinases (p38MAPK) are a group of evolutionary conserved protein kinases which are central for cell adaptation to environmental changes as well as for immune response, inflammation, tissue regeneration and tumour formation. The interest in this group of protein kinases has grown continually since their discovery. Recent studies using new genetic and pharmacological tools are providing helpful information on the function of these stress-activated protein kinases and show that they have an acute impact on the development of prevalent diseases related to inflammation, diabetes, neurodegeneration, and cancer. In this Special Issue we present novel advances and review the knowledge on the identification of p38MAPK substrates, functions, and regulation; mechanisms underlying the role of p38MAPK in malignant transformation and other pathologies; and therapeutic opportunities associated with regulation of p38MAPK activity. |
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2. |
Record Nr. |
UNINA9910254989403321 |
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Titolo |
Advances in Service-Oriented and Cloud Computing : Workshops of ESOCC 2015, Taormina, Italy, September 15-17, 2015, Revised Selected Papers / / edited by Antonio Celesti, Philipp Leitner |
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Pubbl/distr/stampa |
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Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 |
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ISBN |
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Edizione |
[1st ed. 2016.] |
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Descrizione fisica |
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1 online resource (XV, 454 p. 174 illus.) |
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Collana |
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Communications in Computer and Information Science, , 1865-0937 ; ; 567 |
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Disciplina |
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Soggetti |
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Software engineering |
Computer networks |
Business information services |
Application software |
Software Engineering |
Computer Communication Networks |
IT in Business |
Computer and Information Systems Applications |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Nota di contenuto |
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Limits and /or advantages of existing cloud solutions -- Future Internet technologies -- Efficient and adaptive deployment and management of service-based applications across multiple clouds -- Novel cloud service migration practices and solutions -- Digitization of enterprises in the cloud computing era -- Federated cloud networking services. |
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Sommario/riassunto |
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This volume contains the technical papers presented in the seven high-quality workshops associated with the European Conference on Service-Oriented and Cloud Computing, ESOCC 2015, held in Taormina, Italy, in September 2015: Third International Workshop on Cloud for IoT (CLloT 2015), 5th International Workshop on Adaptive Services for the Future Internet (WAS4FI 2015), Second Workshop on Seamless Adaptive Multi-cloud Management of Service-Based Applications (SeaClouds 2015), First International Workshop on Cloud |
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Adoption and Migration (CloudWay 2015), First International Workshop on Digital Enterprise Architecture and Engineering (IDEA 2015), First Workshop on Federated Cloud Networking (FedCloudNet 2015). Abstracts of the presentations held at the European Projects Forum (EU Projects 2015) are included in the back matter of this volume. The 25 full papers and 6 short papers were carefully reviewed and selected from 48 submissions. They focus on specific topics in service-oriented and cloud computing domains such as limits and /or advantages of existing cloud solutions, Future Internet technologies, efficient and adaptive deployment and management of service-based applications across multiple clouds, novel cloud service migration practices and solutions, digitization of enterprises in the cloud computing era, federated cloud networking services. |
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