1.

Record Nr.

UNINA9910254474003321

Titolo

Salivary Gland Development and Regeneration [[electronic resource] ] : Advances in Research and Clinical Approaches to Functional Restoration / / edited by Seunghee Cha

Pubbl/distr/stampa

Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017

ISBN

9783319435138

Edizione

[1st ed. 2017.]

Descrizione fisica

1 online resource (XIII, 263 p. 52 illus., 47 illus. in color.)

Disciplina

617.6

Soggetti

Dentistry

Oral surgery

Maxillofacial surgery

Biomedical engineering

Stem cells

Oral and Maxillofacial Surgery

Biomedical Engineering/Biotechnology

Stem Cells

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di bibliografia

Includes bibliographical references.

Nota di contenuto

Updates on Salivary Gland Development: Salivary Gland Development -- Systems Analysis of Salivary Gland Development and Disease -- The Roles of Mucins in Salivary Gland Development and Regeneration. Glandular Damage and Cell Replacement Therapy: Salivary Gland Resident Stem Cells -- Adult Stem Cells with Special Emphasis on Mesenchymal Stem Cells -- Cellular and Nuclear Reprogramming of Mesenchymal Stem Cells. Bioengineering of Salivary Glands: Current Cell Models for Bioengineering Salivary Glands -- 3D Organ Culture and Matrix Biology -- Clinical Application of 3D Printing Technology in Craniofacial Plastic Surgery and Salivary Gland Regeneration -- Functional Salivary Gland Regeneration by Organ Replacement Therapy -- Therapeutic Considerations for Functional Salivary Gland Restorations: Regulation of Salivary Secretion -- Gene Therapy in Experimental and Clinical Trials -- Surgical Approaches to Functional



Restoration of Saliva Secretion.

Sommario/riassunto

This book provides a comprehensive update on the latest information and knowledge which emerged from translational and basic science research endeavors, targeting the regeneration of salivary glands. The coverage includes salivary gland growth and development, stem cell therapy, bioengineering of salivary glands, and perspectives on and practical approaches to restoration of secretory function. More specifically, among the individual topics addressed are the various types of stem cell of value for cell replacement therapy, technological advances with respect to 3D printing, gene therapy, organ culture of salivary glands, and surgical aspects of the feasibility and practicality of transplantation. Readers will find helpful practical guidance on functional restorations of damaged salivary glands and stimulating insights into potential future directions in salivary gland regeneration research. The authors are all acknowledged experts from a range of academic and clinical backgrounds. Accordingly, the book will be of interest not only to clinicians, such as general dental practitioners, oral medicine specialists, and surgeons who manage dry mouth patients, but also to biomedical engineers, stem cell researchers, and transplant surgeons.