1.

Record Nr.

UNINA9910254324303321

Autore

Mitra Kunal

Titolo

Short Pulse Laser Systems for Biomedical Applications / / by Kunal Mitra, Stephanie Miller

Pubbl/distr/stampa

Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017

ISBN

3-319-54253-2

Edizione

[1st ed. 2017.]

Descrizione fisica

1 online resource (VII, 49 p. 26 illus., 9 illus. in color.)

Collana

SpringerBriefs in Applied Sciences and Technology, , 2191-530X

Disciplina

621.366

Soggetti

Biomedical engineering

Lasers

Photonics

Cancer - Research

Nanotechnology

Biomedical Engineering and Bioengineering

Biomedical Engineering/Biotechnology

Optics, Lasers, Photonics, Optical Devices

Cancer Research

Nanotechnology and Microengineering

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Introduction -- Short Pulse Laser Imaging -- Short Pulse Laser Based Thermal Therapy -- Use of Nanoparticles to Optimize Short Pulse Laser Based Biomedical Applications.

Sommario/riassunto

This book presents practical information on the clinical applications of short pulse laser systems and the techniques for optimizing these applications in a manner that will be relevant to a broad audience, including engineering and medical students as well as researchers, clinicians, and technicians. Short pulse laser systems are useful for both subsurface tissue imaging and laser induced thermal therapy (LITT), which hold great promise in cancer diagnostics and treatment. Such laser systems may be used alone or in combination with optically active nanoparticles specifically administered to the tissues of interest for enhanced contrast in imaging and precise heating during LITT.



Mathematical and computational models of short pulse laser-tissue interactions that consider the transient radiative transport equation coupled with a bio-heat equation considering the initial transients of laser heating were developed to analyze the laser-tissue interaction during imaging and therapy. Experiments were first performed to characterize the tissue optical properties needed to optimize the dose for thermal therapy. Experiments were then performed on animal models to characterize the heat affected zone for LITT. The experimental measurements were also validated using the computational models. .