Connective Tissue Disease : A Comprehensive Guide - Volume 1 / / edited by Dario Roccatello, Lorenzo Emmi

• Record Nr.: UNINA9910254264903321
• Pubbl/distr/stampa: Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016
• ISBN: 3-319-24535-X
• Edizione: [1st ed. 2016.]
• Descrizione fisica: 1 online resource (399 p.)
• Collana: Rare Diseases of the Immune System, , 2282-6505
• Disciplina: 616.77
• Soggetti: Rheumatology; Antibodies; Nephrology
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Part 1 Systemic Lupus Erythematosus -- Introduction - SLE in 21st Century -- Epidemiologic aspects of SLE -- Immunopathogenesis of SLE -- Clinical aspects in SLE -- Autoantibodies and biomarkers: diagnostic aspects -- Joint involvement in Systemic Lupus Erythematosus -- Cutaneous manifestations of SLE -- Kidney Involvement in SLE -- NPSLE -- Cardiovascular issues in SLE -- SLE and Pregnancy -- Vitamin D endocrine system and SLE -- The impact of aPL detection on pregnancy -- SLE and APS -- Disease activity indices and prognosis of SLE -- Conventional therapy for SLE -- Biological Therapy in SLE -- Part 2 Sjögren Syndrome -- Classification criteria for Sjögren syndrome -- Pathogenesis of Sjögren syndrome -- Autoantibodies in Sjögren syndrome and laboratory markers -- Parotid and Submandibular involvement in Sjögren syndrome -- Extraglandular involvement in Sjögren syndrome -- Dry eye in Sjögren syndrome: diagnostic tools and therapy -- Neurologic involvement in Sjögren syndrome -- Lymphoproliferative disorder in Sjögren syndrome -- Pathogenetic aspects of Sjogren Syndrome: Relationships with Cryoglobulinemia and Lymphoproliferation -- Systemic treatment of Sjögren syndrome.
• Sommario/riassunto: In this volume devoted to systemic lupus erythematosus (SLE) and Sjögren syndrome, leading specialists from different disciplines present ; the latest research findings on many aspects of the diseases and describe the most recent trends in treatment, such as the “treat to target” approach. Both basic science and clinical medicine are addressed, with emphasis on the most promising clinical and laboratory-based studies. The coverage is comprehensive in scope, encompassing, for example, epidemiology, pathogenesis, autoantibodies and biomarkers, disease manifestations, involvement of different organs or systems, relationships with other disorders, biological therapy of SLE, and systemic treatment of Sjögren syndrome. Readers will find this first volume of Connective Tissue Disease to be an excellent source of information on the current understanding of, and clinical approach to, SLE and Sjögren syndrome that clearly conveys the progress made in recent years.