1.

Record Nr.

UNINA9910254053003321

Titolo

Measuring Biological Impacts of Nanomaterials / / edited by Joachim Wegener

Pubbl/distr/stampa

Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016

ISBN

3-319-24823-5

Edizione

[1st ed. 2016.]

Descrizione fisica

1 online resource (221 p.)

Collana

Bioanalytical Reviews, , 1867-2086 ; ; 5

Disciplina

620.5

Soggetti

Analytical chemistry

Nanochemistry

Biochemistry

Medicine

Biophysics

Biological physics

Biotechnology

Analytical Chemistry

Biochemistry, general

Biomedicine, general

Biological and Medical Physics, Biophysics

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references at the end of each chapters and index.

Nota di contenuto

Standardized Physical Characterization of Nanoscale Particles: Towards a Bar Code for Nanomaterials -- Bioanalytical Aspects for the detection of nanoparticle effects on cells -- Interactions of Nanoscale Particles with the Air-Water Interface: Implications for Lung Effects of Nanomaterials -- Carbon Dots: Synthesis, Characterization and Bioanalytical Applications -- Changes in Motility of Cultured Cells caused by Nanoparticle Encounter -- Cellular Response to Nano- and Mesoscale Particles probed by Label-free Detection Techniques.

Sommario/riassunto

This book reviews several aspects of the biological response to nanoscale particles on a molecular and cellular level. Nanoscale materials and nanoscale particles in particular have interesting



properties and beneficial applications. While they thus have entered our daily lifes on many different levels (from electronics, over textiles, packaging or surface modifications, to biomedical applications), general rules describing their interaction with biological structures and biological matter are still difficult to derive. The existing literature suggests a variety of interaction schemes between nanoparticles and biological objects, not dispelling the public concerns about possible health effects and harmful properties. A systematic approach to the problem is needed and timely. This book specifically emphasizes bioanalytical problems starting from the characterization of the nanomaterials to the pitfalls and potential artifacts of state-of-the-art cytotoxicity assays that are frequently used to study harmful effects on cells. It also highlights the application of label-free bioanalytical techniques that can potentially complement the present approaches and hence provide new perspectives on this highly discussed cutting-edge field of research and public concern.