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Record Nr. |
UNINA9910254047703321 |
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Titolo |
Novel Therapeutic Approaches to the Treatment of Parkinson’s Disease : An Overview and Update / / edited by Corey R. Hopkins |
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Pubbl/distr/stampa |
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Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 |
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ISBN |
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Edizione |
[1st ed. 2016.] |
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Descrizione fisica |
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1 online resource (VII, 151 p. 20 illus., 10 illus. in color.) |
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Collana |
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Topics in Medicinal Chemistry, , 1862-2461 ; ; 18 |
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Disciplina |
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Soggetti |
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Medicinal chemistry |
Medical biochemistry |
Proteins |
Molecular biology |
Neurochemistry |
Medicinal Chemistry |
Medical Biochemistry |
Receptors |
Molecular Medicine |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di bibliografia |
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Includes bibliographical references at the end of each chapters and index. |
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Nota di contenuto |
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Adenosine A2A Receptor Antagonists -- Targeting α-Synuclein as a Parkinson’s Disease Therapeutic -- Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors. |
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Sommario/riassunto |
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Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and |
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validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors. |
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