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Record Nr. |
UNINA9910253955303321 |
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Titolo |
Chromogranins: from Cell Biology to Physiology and Biomedicine / / edited by Tommaso Angelone, Maria Carmela Cerra, Bruno Tota |
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Pubbl/distr/stampa |
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Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 |
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ISBN |
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Edizione |
[1st ed. 2017.] |
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Descrizione fisica |
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1 online resource (IX, 267 p. 16 illus., 4 illus. in color.) |
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Collana |
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UNIPA Springer Series, , 2366-7516 |
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Disciplina |
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Soggetti |
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Human physiology |
Physiology |
Molecular biology |
Human Physiology |
Animal Physiology |
Molecular Medicine |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di bibliografia |
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Includes bibliographical references at the end of each chapters and index. |
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Nota di contenuto |
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Chromaffin cells and Granins: History and Perspectives -- The extended granin family: structure, function, and biomedical implications -- CgA and CgB in granule secretion -- Proteolytic processing of CgA and CgB/Antimicrobial properties of Chromogranins -- Chromogranins and inositol 1,4,5-trisphosphate-dependent Ca2+-signaling -- CgA in angiogenesis and tumor biology -- Full length CgA: a multifaceted protein in cardiovascular health and disease -- Physio-pharmacological aspects of three Chromogranin A-derived peptides: Vasostatin, Catestatin, and Serpinin -- Comparative aspects of CgA-derived peptides in cardiac homeostasis -- Molecular and cellular mechanisms of action of CgA-derived peptides in cardiomyocytes and endothelial cells -- CgA-derived peptides in pre- and post-conditioning cardioprotection -- Catestatin in physiopathology -- Serpinin: from biosynthesis to cell biology and physiopathology -- Pancreastatin and metabolism -- Chromogranins and the quantum release of catecholamines. |
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Sommario/riassunto |
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The volume is designed to provide an integrated overview of the results from the last fifteen years of research on Chromogranins in relation to cell biology, physiology and biomedicine. The different chapters highlight novel activities of these proteins, including their role in granule biogenesis, hormone co-storage, stimulus-processing-secretion coupling, autonomic sympathetic/parasympathetic balance, immune and cardiocirculatory function, and the response to stress. Biomedical aspects are also illustrated with focus on the prognostic and diagnostic significance of Chromogranin in the presence of tumors, cardiovascular diseases and inflammatory conditions. The volume is of interest for laboratory and clinical scientists, PhD and Post-doc students that will be inspired to go deep inside the molecular, biochemical, physiological, pharmacological and clinical aspects of these fascinating multifaceted proteins. |
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2. |
Record Nr. |
UNINA9910765481903321 |
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Autore |
Savigar-Shaw Leanne |
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Titolo |
Policing Distracted Driving : Contemporary Challenges in Roads Policing / / by Leanne Savigar-Shaw, Helen Wells |
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Pubbl/distr/stampa |
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Cham : , : Springer International Publishing : , : Imprint : Palgrave Macmillan, , 2023 |
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ISBN |
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Edizione |
[1st ed. 2023.] |
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Descrizione fisica |
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1 online resource (168 pages) |
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Collana |
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Palgrave's Critical Policing Studies, , 2730-5368 |
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Disciplina |
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Soggetti |
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Criminology |
Criminal behavior |
Crime |
Technology |
Social psychology |
Criminal law |
Crime Control and Security |
Criminal Behavior |
Crime and Technology |
Social Psychology |
Criminal Law and Criminal Procedure Law |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Chapter 1 – Introduction and purpose -- Chapter 2 - The mobile phone distraction problem and responses to it -- Chapter 3 - Keeping up, staying in touch, getting on -- Chapter 4 – Navigating risk -- Chapter 5 - The ‘law-abiding offender’ -- Chapter 6 - Legitimacy, fairness and distracted driving -- Chapter 7 – Conclusion. |
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Sommario/riassunto |
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This book draws on original research and existing theoretical perspectives and frameworks to critically examine the role of roads policing and its place within the wider field of policing. It looks at the challenges and complexities of doing roads policing and experiencing roads policing from the perspectives of police officers and the public. It uses distracted driving, and more specifically mobile phone use, as an evidence-based case study for a common issue to examine the contribution it makes to collisions, and the challenges of policing it as a driver behaviour. It also discusses broader issues such as the role of roads policing, police legitimacy, the interpretation of law, the interpretation of risk and generating compliance with the law. It speaks to both policing scholars and practitioners, as well as policy makers and road safety organisations. Leanne Savigar-Shaw is Senior Lecturer in Policing at Staffordshire University, UK. After completing a BSc and MSc in Psychology, she progressed to a PhD in Criminology focusing upon driver education and mobile phone use by drivers. She has since been involved in a number of research projects concerning mobile phone use by drivers, speeding, road safety, police legitimacy and procedural justice, and has wider research interests in the policing of the roads. Helen Wells is Senior Lecturer in Criminology at the University of Keele, UK. After completing a BA and MA in Criminology, she progressed to a PhD in Criminology focusing on the public debate around the use of speed cameras. Helen has been researching roads policing for over 20 years and has completed funded projects on topics such as ANPR, speed cameras, ‘dash cam’ evidence submission, uninsured driving, PCC attitudes to roads policing, and distracted driving. |
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