1.

Record Nr.

UNINA9910253898703321

Titolo

Circadian Clocks: Role in Health and Disease / / edited by Michelle L. Gumz

Pubbl/distr/stampa

New York, NY : , : Springer New York : , : Imprint : Springer, , 2016

ISBN

1-4939-3450-3

Edizione

[1st ed. 2016.]

Descrizione fisica

1 online resource (382 p.)

Collana

Physiology in Health and Disease, , 2625-252X

Disciplina

612.022

Soggetti

Human physiology

Medical biochemistry

Nephrology

Cardiology

Psychiatry

Human Physiology

Medical Biochemistry

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references at the end of each chapters and index.

Nota di contenuto

Introduction and Mechanism of the Circadian Clock -- Circadian Rhythms in the Endocrine System -- Circadian Regulation of Sleep -- Circadian Rhythms in Neurological Disease -- Role of the Clock in Metabolism and Obesity -- Circadian Control of Renal Function -- Circadian Rhythms in the Vasculature -- The Cardiac Clock -- Regulation of Immunity by the Circadian Clock -- Rhythms in the Gastrointestinal System -- Chronotherapy in the Treatment of Cancer -- Chronotherapy in the Treatment of Hypertension.-The Circadian Clock as a Drug Target.-.

Sommario/riassunto

This book sheds new light on the molecular mechanisms that generate circadian rhythms. It examines how biological rhythms influence physiological processes such as sleep, hormone synthesis and secretion, immunity, kidney function, the cardiovascular system, blood pressure, and the digestive system. Clinical implications are considered while exploring the impact of rhythms on neuropsychiatric disorders and chronotherapy’s potential for reducing cardiovascular risk. Offering



a cross-section of expertise in both basic and translational (bench-to-bedside) research, this book serves as a guide for physicians and scientists who wish to learn more about the impact of circadian rhythms on physiological processes in health and disease. .