1.

Record Nr.

UNINA9910253885703321

Titolo

Epigenetics and Neuroendocrinology : Clinical Focus on Psychiatry, Volume 1 / / edited by Dietmar Spengler, Elisabeth Binder

Pubbl/distr/stampa

Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016

ISBN

3-319-24493-0

Edizione

[1st ed. 2016.]

Descrizione fisica

1 online resource (280 p.)

Collana

Epigenetics and Human Health, , 2191-2262

Disciplina

598.2188

Soggetti

Neurosciences

Human genetics

Endocrinology 

Human Genetics

Endocrinology

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references at the end of each chapters.

Nota di contenuto

Foreword by Dietmar Spengler & Elisabeth Binder -- Part I, Epigenetics And The Stress System -- I.1 From vulnerability to neurotoxicity: A developmental approach to the effects of stress on brain and behavior  -- I.2 Dynamic regulation of chromatin modification and transcription by GR and the steroid receptors  -- I.3 NR receptor coactivators -- I.4 Glucocorticoid-dependent epigenetic regulation of Fkbp5 -- I.5 Epigenetic programming of the HPA axis by early-life adversity -- I.6 Epigenetic programming of hypothalamic Pomc regulates feeding and obesity -- I.7 Effects of maternal care in monkeys -- I.8 Stress, transposons and the brain epigenome -- Part II; Epigenetics And Sexual Differentiation -- II.1 Neuroepigenetics of sexual differentiation of brain and behavior -- II.2 Differential regulation of androgen receptor and DNA methylation in songbirds -- II.3 chapter title "GnRH gene/Kiss gene, sexual dimorphism, puberty. .

Sommario/riassunto

The field of neuroendocrinology has extended from the initial interest in the hypothalamic control of pituitary secretion to embrace multiple reciprocal interactions between the central nervous system and endocrine systems in the coordination of homeostasis and various



physiological responses from adaptation to disease. Most recently, epigenetic mechanisms were recognized for their role in the development of the neuroendocrine axes as well as in the mediation of gene-environment interactions in stress-related psychiatry disorders.