1.

Record Nr.

UNINA9910253875303321

Titolo

Epigenetics and Neuroendocrinology : Clinical Focus on Psychiatry, Volume 2 / / edited by Dietmar Spengler, Elisabeth Binder

Pubbl/distr/stampa

Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016

ISBN

3-319-29901-8

Edizione

[1st ed. 2016.]

Descrizione fisica

1 online resource (276 p.)

Collana

Epigenetics and Human Health, , 2191-2270

Disciplina

610

Soggetti

Neurosciences

Medical genetics

Endocrinology

Neuroscience

Medical Genetics

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di contenuto

PART III; EPIALLELES AND NEUROENDOCRINOLOGY  -- III.1 Fkbp5 epiallels -- III.2 Genomic regulation of the PACAP receptor, PAC1, and implications for psychiatric disease -- III.3 Prodynorphin epialleles -- PART IV;TRANSGENERATIONAL REGULATION OF THE NEUROENDOCRINE SYSTEM -- IV.1 Epigenetic Risk Factors for Diseases: A Transgenerational Perspective -- IV.2 Epigenetic alteration to NR3C1 and HSD11B2 and the developmental origins of mental disease risk -- IV.3 Intergenerational effects of PTSD on offspring glucocorticoid receptor methylation -- PART V; EPIGENETIC BIOMARKERS AND NEUROENDOCRINOLOGY -- V.1 Epigenetic biomarkers for early life adversity -- V.2 Epigenetic biomarkers of maternal stress -- V.3 Epigenetic modifications in borderline personality disorder -- V.4 Oxytocin receptors and neurobehavior -- V.5 Psychosocial stress and DNA methylation.

Sommario/riassunto

The field of neuroendocrinology has extended from the initial interest in the hypothalamic control of pituitary secretion to embrace multiple reciprocal interactions between the central nervous system (CNS) and endocrine systems in the coordination of homeostasis and various



physiological responses from adaptation to disease. Most recently, epigenetic mechanisms were recognized for their role in the development of the neuroendocrine axes as well as in the mediation of gene-environment interactions in stress-related psychiatry disorders.