1.

Record Nr.

UNINA9910253869403321

Titolo

Non-coding RNA and the Reproductive System [[electronic resource] /] / edited by Dagmar Wilhelm, Pascal Bernard

Pubbl/distr/stampa

Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2016

ISBN

94-017-7417-X

Edizione

[1st ed. 2016.]

Descrizione fisica

1 online resource (201 p.)

Collana

Advances in Experimental Medicine and Biology, , 0065-2598 ; ; 886

Disciplina

572.88

Soggetti

Medical genetics

Developmental biology

Reproductive medicine

Gene Function

Developmental Biology

Reproductive Medicine

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references at the end of each chapters and index.

Sommario/riassunto

This book provides an overview of the role and function of regulatory RNAs that lack protein-coding potential in key reproductive tissues. This includes the role of small interfering RNAs (siRNAs), microRNAs (miRNAs), PIWI-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs) and long non-coding RNAs (lncRNAs). Through clear, detailed and comprehensive debate, international leading experts discuss the role these novel regulators in normal development of sexual dimorphisms, including the differentiation of ovaries and testes, the genital tract including prostate, epididymis and uterus, as well as mammary glands. In addition, particular attention is paid on their role in pathophysiological processes within the reproductive tract. The power of next generation sequencing has proved to be an invaluable tool to discover new non-coding RNAs. While the identification of non-coding RNA is relatively easy, analysing their function represents still a challenge today. In this book, authors present historical and conceptual background information, highlight the ways in which non-coding RNAs



function is analysed and present their vision of the future research in their key research area.