1.

Record Nr.

UNISA990000047810203316

Autore

SCHARF, Michael P.

Titolo

Balkan justice : the story behind the first international war crimes trial since Nuremberg / Michael P. Scharf

Pubbl/distr/stampa

Durham : Carolina Academic : copyr. 1997

ISBN

0-89089-918-5

Descrizione fisica

XVII, 340 p. ; 23 cm

Disciplina

341.690268

Collocazione

XXIII.1.L. 313 (IG VIII 9 560)

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

2.

Record Nr.

UNISA996213129003316

Autore

Fearn David

Titolo

Aegina: Contexts for Choral Lyric Poetry: Myth, History, and Identity in the Fifth Century BC

Pubbl/distr/stampa

Oxford, : Oxford University Press, 2011

ISBN

0-19-159492-X

0-19-954651-7

Descrizione fisica

1 online resource (xvi, 511 p.)

Classificazione

6,12

FE 1375

Altri autori (Persone)

FearnDavid

Disciplina

938.5

Soggetti

Regions & Countries - Europe

History & Archaeology

Greece

Kongress2006.Oxford

Criticism, interpretation, etc.

History

Aegina Island (Greece) Antiquities

Aegina Island (Greece) Civilization

Aegina Island (Greece) History

Aegina Island (Greece) In literature



Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Bibliographic Level Mode of Issuance: Monograph

Nota di bibliografia

Includes bibliographical references.

Nota di contenuto

; Introduction : Aegina in contexts / David Fearn -- Contexts for heroic myth-making : ethnicity, inter-state relations, cult, and commerce. Asopos and his multiple daughters : traces of preclassical epic in the Aeginetan odes of Pindar / Gregory Nagy ; Rethinking the Sanctuary of Aphaia / James Watson ; The Theārion of the Pythian one : the Aeginetan Thēaroi in context / Ian Rutherford ; Musical merchandise "on every vessel" : religion and trade on Aegina / Barbara Kowalzig -- Poetry, performance, politics. Aeginetan Epinician culture : naming, ritual, and politics / David Fearn ; Aeginetan odes, reperformance, and Pindaric intertextuality / Andrew Morrison -- Interfaces between poetry, myth, and art. Giving wings to the Aeginetan sculptures : the Panhellenic aspirations of Pindar's Eighth Olympian / Lucia Athanassaki ; Thebes, Aegina, and the Temple of Aphaia : a reading of Pindar's Isthmian 6 / Henrik Indergaard ; The Trojan War, Theoxenia, and Aegina in Pindar's Paean 6 and the Aphaia sculptures / Guy Hedreen -- The historiographical aftermath. Herodotus of Aeginetan identity / Elizabeth Irwin ; Lest the things done by men become exitēla : writing up Aegina in a late fifth-century context / Elizabeth Irwin.

Sommario/riassunto

A collection of essays dealing with different aspects of the fifth-century BC history and culture of the Greek island of Aegina, famous for its magnificent architecture and sculpture and for its inhabitants' patronage of some of the greatest Classical poets.



3.

Record Nr.

UNINA9910220059703321

Autore

Kristin Zorn

Titolo

Inhibiting PARP as a Strategic Target in Cancer

Pubbl/distr/stampa

Frontiers Media SA, 2016

Descrizione fisica

1 online resource (97 p.)

Collana

Frontiers Research Topics

Soggetti

Medicine

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Sommario/riassunto

Poly-ADP ribose polymerase (PARP) proteins are critical mediators of DNA repair. Many traditional anti-cancer chemotherapy agents overwhelm a cell's ability to repair DNA damage in order to kill proliferating malignant cells. Recent evidence suggests that cancers within and across tissue types have specific defects in DNA repair pathways, and that these defects may predispose for sensitivity and resistance to various classes of cytotoxic agents. Breast, ovarian and other cancers develop in the setting of inherited DNA repair deficiency, and these cancers may be more sensitive to cytotoxic agents that induce DNA strand breaks, as well as to inhibitors of PARP activity. A series of recent clinical trials has tested whether PARP inhibitors can achieve synthetic lethality in hereditary DNA repair-deficient tumors. At the current time, mutation of BRCA serves as a potential, but not comprehensive, biomarker to predict response to PARP inhibitor therapy. Mechanisms of resistance to PARP inhibitors are only recently being uncovered. Future studies seek to identify sporadic cancers that harbor genomic instability rendering susceptibility to PARP inhibitors that compound lethal DNA damage.