1.

Record Nr.

UNINA9910208953303321

Titolo

The genetics of neurodevelopmental disorders / / edited by Kevin J. Mitchell ; contributors, Ayokunmi Ajentunmobi [and twenty three others]

Pubbl/distr/stampa

[Place of publication not identified] : , : Wiley-Blackwell, , 2015

©2015

ISBN

1-118-52499-3

1-118-52497-7

Descrizione fisica

1 online resource (480 p.)

Disciplina

618.9280475

Soggetti

Intellectual disability

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references at the end of each chapters and indexes.

Nota di contenuto

The genetic architecture of neurodevelopmental disorders / Kevin J. Mitchell -- Overlapping etiology of neurodevelopmental disorders / Eric Kelleher and Aiden Corvin -- The mutational spectrum of neurodevelopmental disorders / Nancy D. Merner, Patrick A. Dion and Guy A. Rouleau -- The role of genetic interactions in neurodevelopmental disorders / Jason H. Moore and Kevin J. Mitchell -- Developmental instability, mutation load, and neurodevelopmental disorders / Ronald A. Yeo and Steven W. Gangestad -- Environmental factors and gene-environment interactions / John McGrath -- The genetics of brain malformations / M. Chiara Manzini and Christopher A. Walsh -- Disorders of axon guidance / Heike Blockus and Alain Chédotal -- Synaptic disorders / Catalina Betancur and Kevin J. Mitchell -- Human stem cell models of neurodevelopmental disorders / Peter Kirwan and Frederick J. Livesey -- Animal models for neurodevelopmental disorders / Hala Harony-Nicolas and Joseph D. Buxbaum -- Cascading genetic and environmental effects on development : implications for intervention / Esha Massand and Annette Karmiloff-Smith -- Human genetics and clinical aspects of neurodevelopmental disorders / Gholson J. Lyon and Jason O'Rawe -- Progress toward therapies and interventions for neurodevelopmental



disorders / Ayokunmi Ajentunmobi and Daniela Tropea.