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1. |
Record Nr. |
UNINA9910164952403321 |
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Autore |
Mayer Dale |
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Titolo |
Hide'n go seek / / Dale Mayer |
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Descrizione fisica |
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Collana |
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Classificazione |
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Soggetti |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Sommario/riassunto |
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A twisted game of Hide'n Go Seek forces an unlikely alliance between a no-nonsense FBI agent and a search-and-rescue worker. Celebrated search-and-rescue worker Kali Jordon has hidden her psychic abilities by crediting her canine partner Shiloh with the recoveries. But Kali knows the grim truth—The Sight that she inherited from her grandmother allows her to trace violent energy unerringly to victims of violence. No one knows her secret until a twisted killer challenges her to a deadly game of Hide'n Go Seek that threatens those closest to her. Now she must rely on FBI Special Agent Grant Summers, a man who has sworn to protect her, even as he suspects there's more to Kali and Shiloh than meets the eye. As the killer draws a tighter and tighter circle around Kali, she and Grant find there's no place to hide. Are her visions the key to finding the latest victim alive or will this twisted game of Hide'n Go Seek cost her...everything? |
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2. |
Record Nr. |
UNINA9910349476303321 |
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Titolo |
Chromosome Translocation / / edited by Yu Zhang |
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Pubbl/distr/stampa |
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Singapore : , : Springer Singapore : , : Imprint : Springer, , 2018 |
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ISBN |
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9789811305931 |
981-13-0593-5 |
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Edizione |
[1st ed. 2018.] |
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Descrizione fisica |
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1 online resource (V, 168 p. 29 illus., 27 illus. in color.) |
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Collana |
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Advances in Experimental Medicine and Biology, , 0065-2598 ; ; 1044 |
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Disciplina |
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Soggetti |
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Human genetics |
Cytology |
Human Genetics |
Cell Biology |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di contenuto |
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Chapter 1: Historical and clinical overview of chromosome translocations -- Chapter 2: Next generation sequencing to identify chromosome translocation -- Chapter 3: The experimental models to study chromosome translocations -- Chapter 4: High throughput translocation sequencing to identify mechanistic factors shaping translocatome -- Chapter 5: Live cell imaging to study chromosome translocation -- Chapter 6: CRISPR/Cas9 to induce chromosome translocation in vivo -- Chapter 7: Generation of DNA double strand breaks (DSBs) -- Chapter 8: The role of DSB response pathway in regulating chromosome translocation -- Chapter 9: DSB repair and ligation of chromosome translocation -- Chapter 10: 3D genome organization defines the chromosome translocation pattern -- Chapter 11: Mechanisms of chromosome deletion -- Chapter 12: Chromothripsis: The role of DNA double strand break form on repair pathway selection. |
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Sommario/riassunto |
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This volume discusses various aspects of mechanisms and methodologies of chromosome translocations, ranging from a historical and clinical overview of chromosome translocations to the rapid development of the next-generation sequencing technologies, which |
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has dramatically increased our understanding of the spectrum of chromosome translocations in human diseases. The book also introduces the mechanistic studies on chromosome deletions and their implications in cancer, and discusses the mechanisms of regulating chromothripsis, a unique complex type of chromosome translocation. It is a valuable resource for students and researchers alike, providing insights into chromosome translocations and, potentially, other genomic aberrations involved in understanding and curing human diseases. |
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