1.

Record Nr.

UNINA9910163094003321

Autore

Flint S. Jane

Titolo

Human adenoviruses : from villains to vectors / / Jane Flint, Glen Nemerow

Pubbl/distr/stampa

New Jersey : , : World Scientific, , [2017]

©2017

ISBN

981-310-980-7

Descrizione fisica

1 online resource (416 pages) : illustrations (some color)

Disciplina

579.2/443

Soggetti

Adenoviruses

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

A short history of adenovirus -- Adenovirus composition, structure, and biophysical properties -- Cell attachment and entry -- Intracellular trafficking -- Gene expression -- Replication of the genome -- Capsid assembly, maturation, and egress -- Pathogenesis -- Host defenses -- Antiviral approaches -- Therapeutic applications : history and use of replication-defective vectors -- Therapeutic applications : vaccines and oncolytic vectors.