1.

Record Nr.

UNINA9910163018503321

Titolo

Paediatric thyroidology / / volume editor Gabor Szinnai

Pubbl/distr/stampa

Basel, Switzerland : , : S. Karger AG, , 2014

©2014

ISBN

3-318-02721-9

Descrizione fisica

1 online resource (262 p.)

Collana

Endocrine Development, , 1662-2979 ; ; Volume 26

Disciplina

616.44

Soggetti

Thyroid gland - Diseases

Thyroid gland - Diseases - Diagnosis

Thyroid gland - Diseases - Alternative treatment

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

"51 figures, 17 in color, and 26 tables, 2014"--Cover.

Nota di bibliografia

Includes bibliographical references and indexes.

Nota di contenuto

""Cover""; ""Front Matter""; ""Contents""; ""Preface""; ""Thyroid Hormone Physiology""; ""Evolution, Child Development and the Thyroid: A Phylogenetic and Ontogenetic Introduction to Normal Thyroid Function""; ""Abstract""; ""Making of Thyroid Hormones""; ""Which Was First, the Thyroid Hormone or Its Receptor?""; ""Metamorphosis Matters""; ""The Appearance of the Gland""; ""Losing Thyroid Self-Control: The Pituitary Takes Over""; ""Evolution of Thyroid Hormone Function in Humans""; ""Thyroid Hormones and Human Brain Development""; ""Acknowledgement""; ""References""

""Human Fetal Thyroid Function""""Abstract""; ""Development of the Normal Thyroid Gland""; ""Early Human Fetal Thyroid Function: First Trimester""; ""Late Human Fetal Thyroid Function: After the First Trimester""; ""Examples of Primary Human Fetal Thyroid Dysfunction: Down Syndrome and Hormonosynthesis Defects""; ""Conclusion""; ""Acknowledgments""; ""References""; ""The Role of Thyroid Hormones for Brain Development and Cognitive Function""; ""Abstract""; ""Thyroid Hormone Action in Brain Development: Animal Evidence""; ""Maternal Thyroid Hormone Is Necessary for Early Brain Development""

""What Happens when the Maternal Thyroid Hormone Supply Is Insufficient?""""What Happens when the Infant�s Thyroid Hormone Supply Is Insufficient?""; ""Maternal Hypothyroidism and Congenital



Hypothyroidism: Distinct Models of Thyroid Hormone Loss at Different Times in Development""; ""Conclusion""; ""References""; ""Congenital Hypothyroidism""; ""Neonatal Screening for Congenital Hypothyroidism""; ""Abstract""; ""History of Neonatal Screening for Congenital Hypothyroidism""; ""Screening Organization""; ""Screening Strategy""; ""Screening Protocols""

""Confirmation of Congenital Hypothyroidism""""Follow-Up""; ""Conclusion""; ""References""; ""Neonatal Screening for CongenitalHypothyroidism""; ""Abstract""; ""History of Neonatal Screening for Congenital Hypothyroidism""; ""Screening Organization""; ""Screening Strategy""; ""Screening Protocols""; ""Confirmation of Congenital Hypothyroidism""; ""Follow-Up""; ""Conclusion""; ""References""; ""Diagnosis, Treatment and Outcome ofCongenital Hypothyroidism""; ""Abstract""; ""Diagnosis""; ""Treatment""; ""Outcome""; ""Mild Isolated Hyperthyrotropinemia""; ""Acknowledgments""; ""References""

""Clinical Genetics of CongenitalHypothyroidism""""Abstract""; ""Thyroid Dysgenesis""; ""Thyroid Dyshormonogenesis""; ""Frequency of Monogenetic Forms of CH""; ""Conclusions: Why Genetics?""; ""Acknowledgements""; ""References""; ""Central Hypothyroidism in Children""; ""Abstract""; ""Neonatal Screening Programs for Central Congential Hypothyroidism""; ""Central Control of Thyroid Function: Hormonal and Molecular Actors""; ""Animal and Cellular Models of Central Hypothyroidism""; ""Central Hypothyroidism in Pediatrics""; ""Clinical Forms of Human Central Hypothyroidism""

""Conclusions and Perspectives""

Sommario/riassunto

This book presents a comprehensive overview of pediatric thyroid diseases and thus provides a useful tool for clinical problem solving. Opinion leaders in the field present reviews on all relevant diseases of the hypothalamic-pituitary-thyroid axis. Sixteen chapters cover topics ranging from fetal thyroidology, congenital hypothyroidism, central hypothyroidism, inherited defects of thyroid hormone action, cell transport and metabolism to iodine deficiency, autoimmune thyroid disease and thyroid tumors.   Written by clinicians, the chapters provide in-depth information and current guidelines for clinical problems encountered in pediatric thyroidology. As a unique feature, a case seminar collection for each chapter presents typical patient histories providing key learning points and key references for clinical problem solving in family medicine, pediatric endocrinology and medical genetics.  Providing a succinct update on clinical pediatric thyroidology, this book is an essential tool for pediatric and adult endocrinologists, as well as for general practitioners, pediatricians and medical geneticists.



2.

Record Nr.

UNISA996290136103316

Titolo

Transportation research record

Pubbl/distr/stampa

Washington, : Transportation Research Board, Commission on Sociotechnical Systems, National Research Council, National Academy of Sciences

ISSN

2169-4052

Classificazione

55.29

Disciplina

380

380.5/08

Soggetti

Transportation

Roads

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Periodico

Note generali

Journal of the Transportation Research Board.

Refereed/Peer-reviewed