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1. |
Record Nr. |
UNINA9910137235403321 |
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Autore |
Mark Christopher Coles |
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Titolo |
Emerging immune functions of non-hematopoietic stromal cells / / topic editors: Christopher G. Mueller, Paul Kaye, Mark C. Coles and Burkhard Ludewig |
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Pubbl/distr/stampa |
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Frontiers Media SA, 2014 |
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Switzerland : , : Frontiers Media SA, , 2014 |
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ISBN |
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Descrizione fisica |
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1 online resource (161 pages) : illustrations |
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Collana |
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Frontiers Research Topics |
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Disciplina |
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Soggetti |
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Clinical Immunology |
Medicine |
Health & Biological Sciences |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Bibliographic Level Mode of Issuance: Monograph |
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Nota di bibliografia |
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Includes bibliographical references. |
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Sommario/riassunto |
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The development and function of the immune system is dependent on interactions between haematopoietic cells and non-hematopoietic stromal cells. The non-hematopoietic stromal cells create the microenvironment in which the immune system operates, providing an architectural landscape for hematopoietic cell-cell interactions and molecular cues governing haematopoietic cell positioning, growth and survival. Not surprisingly, therefore, aberrant stromal cell function has recently been shown to play a key role in the development of disease pathologies associated with immune dysfunction. For example, remodelling of lymphoid tissue stroma and the development of ectopic tertiary lymphoid tissues are characteristic of many infectious and inflammatory diseases and stromal cells have a recognised role in lymphoma and tumour development and resistance to therapy. An increased understanding of the molecular basis of stromal cell differentiation and function in these varied contexts will provide new tools to promote research on stromal cell biology and immune dysfunction, and potential new targets for therapeutic intervention in diseases with a major impact on public health. The importance of |
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stromal cells and the molecular mechanisms of stromal cell function in the regulation of immune responses have only recently been appreciated and thus represent an exciting new area in immunology. |
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2. |
Record Nr. |
UNINA9910155585403321 |
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Autore |
DeMoss Nancy Leigh |
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Titolo |
Surrender : The Heart God Controls |
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ISBN |
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Disciplina |
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Formato |
Musica |
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Livello bibliografico |
Monografia |
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Sommario/riassunto |
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For a Christian, waving the white flag doesn't mean, "I give up!" It means, "Victory at last!" Struggling with stubborn habits? Secret sin? Spiritual strongholds? The key isn't how committed you are to the battle-it's how surrendered you are to God. This truth can be your breakthrough, the first step towards a deeper, richer, victorious spiritual life. With her compelling mix of profound biblical insight and personal example, Nancy Leigh DeMoss reveals why it is only when you surrender your heart, your soul, your body, your ambitions-everything-to God that He can fully help you triumph. You can win that battle. You can have that victory. But not until you learn to surrender.Surrender is the second book in The Revive Our Hearts Series, which has sold well over 240,000 copies! With study questions at the end of each chapter, it is ideal for personal or small group study. |
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