1.

Record Nr.

UNINA9910154884303321

Titolo

Applied surrogate endpoint evaluation methods with SAS and R / / Ariel Alonso, Theophile Bigirumurame, Tomasz Burzykowski, Marc Buyse, Geert Molenberghs, Leacky Muchene, Nolen Joy Perualila, Ziv Shkedy, Wim Van der Elst

Pubbl/distr/stampa

Boca Raton : , : CRC Press, , [2017]

©2017

ISBN

1-315-35536-1

1-315-37266-5

1-4822-4937-5

Edizione

[1st ed.]

Descrizione fisica

1 online resource (396 pages) : illustrations

Collana

Chapman & Hall/CRC Biostatistics Series

Disciplina

610.72

Soggetti

Clinical trials - Statistical methods

Medicine - Research - Methodology

R (Computer program language)

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

A Chapman and Hall book.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

I. Introductory material -- II. Contemporary surrogate endpoint evaluation methods : multiple-trial methods -- III. Software tools -- IV. Additional considerations and further topics.

Sommario/riassunto

When a true endpoint is difficult to use because of such factors as long follow-up times or prohibitive cost, it is sometimes possible to use a surrogate endpoint that can be measured in a more convenient or cost-effective way. This book focuses on the use of surrogate endpoint evaluation methods in practice, using SAS and R.