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Record Nr. |
UNINA9910566471803321 |
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Autore |
Jeon Byeong Hwa |
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Titolo |
Endothelial Dysfunction: From Pathophysiology to Novel Therapeutic Approaches |
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Pubbl/distr/stampa |
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Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
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Descrizione fisica |
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1 online resource (368 p.) |
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Soggetti |
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Biotechnology |
Technology: general issues |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Sommario/riassunto |
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Dear colleagues, This Special Issue, "Endothelial Dysfunction: From Pathophysiology to Novel Therapeutic Approaches", focuses on the pathophysiology of endothelial dysfunction, new biomarkers for endothelial dysfunction related to cardiovascular disorders or tumors, and novel therapeutic approaches for endothelial dysfunctions. Vascular endothelium is an active tissue and plays a crucial role in the maintenance of vascular homeostasis. Chronic exposure to risk factors, such as hypertension, high cholesterolemia, or oxidative stress, induces endothelial dysfunctions and results in a loss of endothelial integrity, smooth muscle cell proliferation, and macrophage recruitment. The pathophysiology of endothelial dysfunction (ED) is complex and multi-factorial factors are involved, such as oxidative stress or chronic inflammation. The primary prevention of cardiovascular risk factors and endothelial dysfunctions, as well as the early detection of or molecular imaging techniques for endothelial dysfunction, helps to prevent the development of cardiovascular disorders. Novel therapeutic approaches or drug delivery systems for endothelial dysfunctions have had promising beneficial effects in preclinical or clinical levels by affecting the progression of atherosclerotic changes, tumor angiogenesis, and host-immune reactions near tumor environments. |
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2. |
Record Nr. |
UNINA9910151860203321 |
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Autore |
Gáspár Péter |
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Titolo |
Robust Control Design for Active Driver Assistance Systems : A Linear-Parameter-Varying Approach / / by Péter Gáspár, Zoltán Szabó, József Bokor, Balazs Nemeth |
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Pubbl/distr/stampa |
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Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 |
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ISBN |
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Edizione |
[1st ed. 2017.] |
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Descrizione fisica |
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1 online resource (XIII, 293 p. 107 illus., 48 illus. in color.) |
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Collana |
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Advances in Industrial Control, , 1430-9491 |
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Disciplina |
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Soggetti |
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Automatic control |
Automotive engineering |
Control and Systems Theory |
Automotive Engineering |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Introduction -- Part I Design Tools -- Modeling for Control -- Performance and Uncertainty -- Robust H-infinity/LPV Control Design -- Hierarchical Control Design -- Part II Vehicle Components and Functions -- Wheel-Orientation Control for Yaw Dynamics -- Torque Control for Yaw Dynamics -- Vertical Dynamics and Control -- Cruise Control in Longitudinal Dynamics -- Part III Integration of Vehicle Systems -- Actuator Selection Methods -- Driver-in-the-Loop Systems -- Integrated Vehicle Control -- Reconfigurable and Fault-Tolerant Control -- Part IV Conclusions. |
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Sommario/riassunto |
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This monograph focuses on control methods that influence vehicle dynamics to assist the driver in enhancing passenger comfort, road holding, efficiency and safety of transport, etc., while maintaining the driver’s ability to override that assistance. On individual-vehicle-component level the control problem is formulated and solved by a unified modelling and design method provided by the linear parameter varying (LPV) framework. The global behaviour desired is achieved by a judicious interplay between the individual components, guaranteed by an integrated control mechanism. The integrated control problem is also formalized and solved in the LPV framework. Most important |
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among the ideas expounded in the book are: application of the LPV paradigm in the modelling and control design methodology; application of the robust LPV design as a unified framework for setting control tasks related to active driver assistance; formulation and solution proposals for the integrated vehicle control problem; proposal for a reconfigurable and fault-tolerant control architecture; formulation and solution proposals for the plug-and-play concept; detailed case studies. Robust Control Design for Active Vehicle Assistance Systems will be of interest to academic researchers and graduate students interested in automotive control and to control and mechanical engineers working in the automotive industry. Advances in Industrial Control aims to report and encourage the transfer of technology in control engineering. The rapid development of control technology has an impact on all areas of the control discipline. The series offers an opportunity for researchers to present an extended exposition of new work in all aspects of industrial control. |
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