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1. |
Record Nr. |
UNINA9910792125203321 |
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Autore |
Kimmelman Jonathan |
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Titolo |
Gene transfer and the ethics of first-in-human research : lost in translation / / Jonathan Kimmelman [[electronic resource]] |
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Pubbl/distr/stampa |
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Cambridge : , : Cambridge University Press, , 2010 |
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ISBN |
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0-511-84765-3 |
1-107-20737-1 |
0-511-64185-0 |
0-511-63941-4 |
0-511-64049-8 |
0-511-63834-5 |
0-511-64236-9 |
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Descrizione fisica |
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1 online resource (xi, 205 pages) : digital, PDF file(s) |
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Disciplina |
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Soggetti |
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Gene therapy - Moral and ethical aspects |
Clinical trials - Moral and ethical aspects |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Title from publisher's bibliographic system (viewed on 05 Oct 2015). |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Introduction: gene transfer lost in translation -- What is gene transfer? -- Safety, values, and legitimacy: the protean nature of risk in translational trials -- Taming uncertainty: risk and gene-transfer clinical research -- Succor or suckers? Benefit, risk, and the therapeutic misconception -- Looking backward: a model value for translational trials -- The chasm: the ethics of initiating first-in-human clinical trials -- Tropic of cancers: gene transfer in resource-poor settings -- Great expectations and hard times: expectation management in gene transfer -- Something in the sight adjusts itself: conclusions. |
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Sommario/riassunto |
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Human gene transfer is widely regarded as one of the most promising technologies for the treatment of a variety of disorders, but it presents practitioners with a variety of difficult ethical questions. Gene Transfer and the Ethics of First-in-Human Research examines the ethical and policy dimensions of testing interventions in human beings for the first time. The book discusses the difficult ethical challenges that arise from attempting to translate laboratory discoveries into clinical applications. |
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These range from which available techniques to use, when to initiate human testing, questions of consent, expectation in public arenas, how to define acceptable risk, and the inclusion of vulnerable or disadvantaged subjects in early phase trials. This book is relevant to ethicists, legal practitioners, policy makers, geneticists and clinicians involved in clinical trials of new medical interventions. |
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2. |
Record Nr. |
UNINA9910148621303321 |
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Autore |
O'Dell Nicole |
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Titolo |
Hot Buttons Image Edition |
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Pubbl/distr/stampa |
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GRAND RAPIDS : , : Kregel Publications, , 2013 |
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©2013 |
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ISBN |
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Edizione |
[1st ed.] |
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Descrizione fisica |
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1 online resource (160 p.) |
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Disciplina |
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Soggetti |
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Self-esteem in adolescence |
Christian teenagers |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di contenuto |
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Cover -- Title Page -- Copyright -- Dedication -- Contents -- Preface -- Acknowledgments -- Part One: Image Hot Buttons -- Chapter 1: Prepared: Answering Why -- Chapter 2: Watchful: Answering When -- Chapter 3: Proactive: Answering How -- Part Two: Identifying the Image Hot Buttons -- Chapter 4: Popularity -- Chapter 5: Self-Esteem -- Chapter 6: Body Image -- Chapter 7: Eating Disorders -- Chapter 8: Celebrities & Media -- Part Three: Pressing the Image Hot Buttons -- Chapter 9: Practical Procedures -- Chapter 10: The Armor of God -- Chapter 11: Strategic Scenarios -- Part Four: Parent-Teen Study Guide -- Chapter 12: Confession -- Chapter 13: Forgiveness -- Chapter 14: Clean Slate -- Recommended Resources -- Notes -- About the Author |
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Sommario/riassunto |
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From dating to drugs, modesty to purity, morals to popularity, teens face all sorts of tough issues. How teens respond to these challenges |
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will influence their future, possibly define their future, maybe even determine whether they have a future or not.Following four successful books in the uniquely packaged Hot Buttons Series, author, mom, and broadcaster, Nicole O'Dell now debuts another book on one of the most prevalent issues in the lives of today's teens: image. Parents can reach for this quick-reference resource to create healthy conversations with their teens about self esteem, piercings and tattoos, eating disorders, and trash talk.Nicole's creative strategic scenarios, discussion questions, and Bible studies have and will continue to equip parents to proactively prepare their tweens and teens to respond to challenges with courage and grace. |
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