1.

Record Nr.

UNINA9910146052003321

Titolo

Drug targeting : organ-specific strategies

Pubbl/distr/stampa

[Place of publication not identified], : Wiley VCH, 2001

ISBN

1-280-64441-9

9786610644414

3-527-60006-X

Descrizione fisica

1 online resource (406 pages)

Collana

Methods and principles in medicinal chemistry  Drug targeting

Disciplina

615/.7

Soggetti

Drug targeting

Drug Delivery Systems

Drug Therapy

Therapeutics

Analytical, Diagnostic and Therapeutic Techniques and Equipment

Pharmacy, Therapeutics, & Pharmacology

Health & Biological Sciences

Electronic books.

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Bibliographic Level Mode of Issuance: Monograph

Sommario/riassunto

How are medicines transported intact through the body to their specific target sites without triggering side effects? The answer is "Drug Targeting". This thoroughly application--oriented book gives comprehensive answers to this and many other questions that confront scientists daily in chemical, pharmaceutical and medical research. A concise overview of the most important basic theories, modern forms of therapy and molecular biological tools, it represents a comprehensible introduction to the topic. The book then goes on to deal with strategies for target applications, divided according to target site, for example brain, lungs, liver, blood vessels and tumor cells. The third part is devoted to special, modern techniques, from phage display methods, via the use of tissue slices right up to pharmacokinetic modeling. Throughout, the focus remains on the practical aspect and



successful application of the method in question, although a glance at what the future holds is also included. A volume that every pharmaceutically oriented research group should own.