Inhibitors in patients with haemophilia [[electronic resource] /] / edited by E.C. Rodriguez-Merchan, C.A. Lee

• Record Nr.: UNINA9910145421403321
• Pubbl/distr/stampa: Osney Mead, Oxford ; ; Malden, MA, : Blackwell Science, c2002
• ISBN: 1-281-32099-4; 9786611320997; 0-470-75726-4; 0-470-75724-8
• Descrizione fisica: 1 online resource (230 p.)
• Altri autori (Persone): Rodriguez-MerchanE. C; LeeChristine A
• Disciplina: 616.1/572
• Soggetti: Hemophilia - Pathophysiology; Hemophilia - Treatment - Complications; Hemophilia - Immunological aspects
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Inhibitors in Patients with Haemophilia; Contents; Contributors; Preface; Part 1: Haematology; 1 Natural history of inhibitors in severe haemophilia A and B: incidence and prevalence; 2 Characterization of inhibitors in congenital haemophilia; 3 Incidence and prevalence of inhibitors and type of blood product in haemophilia A; 4 Genetic basis of inhibitor development in severe haemophilia A and B; Part 2: Management of treatment; 5 Methods: plasmapheresis and protein A immunoadsorption; 6 Venous access in children with inhibitors; Part 3: Immune tolerance; 7 Immune tolerance: high-dose regimen8 Immune tolerance: low-dose regimen; 9 Immune tolerance and choice of concentrates; 10 Immune tolerance: The North American Immune Tolerance Registry; Part 4: Medical management of bleeding episodes; 11 The treatment of bleeding episodes in children; 12 General medical management of bleeding episodes: haemarthroses, muscle haematomas, mucocutaneous bleeding and haematuria; 13 Life- and limb-threatening episodes and intracranial bleeds; Part 5: Inhibitors in ; haemophilia B, inhibitors in mild and moderate haemophilia A and acquired inhibitors to FVIII; 14 Factor IX inhibitors and anaphylaxis15 Inhibitors in mild and moderate haemophilia A; 16 Acquired inhibitors to factor VIII; Part 6: Musculoskeletal issues; 17 Pathogenesis of musculoskeletal complications of haemophilia; 18 Orthopaedic management of haemarthroses; 19 Chemical synoviorthesis; 20 Radiosynoviorthesis in patients with haemophilia and inhibitors; 21 Musculoskeletal magnetic resonance imaging; 22 Treatment of iliopsoas haematomas and compartment syndromes in patients with haemophilia who have a circulating antibody; 23 A rational approach to the treatment of haemophilic blood cyst (pseudotumour) in patients with inhibitors24 Haemophilia patients with inhibitors: a rheumatologist's point of view; 25 Rehabilitation of patients with haemophilia and inhibitors; 26 Physiotherapy in the management of patients with inhibitors; 27 Elective orthopaedic surgery in haemophilia patients with high-responding inhibitors; Part 7: General surgery; 28 General and emergency surgery in patients with high-responding inhibitors; 29 Dental extraction in patients with haemophilia and inhibitors; Part 8: Psychosocial issues; 30 Psychosocial impact of inhibitors on haemophilia patients' quality of lifePart 9: General strategy for management of inhibitor patients; 31 General strategy for management of inhibitor patients (summary); 32 Immunoadsorption with anti-immunoglobulin antibodies using Ig-TheraSorb columns; 33 Standard, high and mega bolus doses of rVIIa or recombinant VIIa: comparison of three different treatment regimens; Index
• Sommario/riassunto: Edited by an orthopaedic surgeon and a haematologist who are leading specialists in the treatment of haemophilia, Inhibitors in Patients with Haemophilia reviews the different haemostatic products and protocols for the control of bleeding and surgery in haemophilic patients with inhibitors. The book draws together in a single volume all of the clinical issues involved in the treatment of inhibitors from numerous specialists worldwide. It will be an invaluable resource for all those treating inhibitors in people with haemophilia.