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Record Nr. |
UNINA9910145018203321 |
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Titolo |
Pathological pain : from molecular to clinical aspects |
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Pubbl/distr/stampa |
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Chichester, UK ; ; Hoboken, NJ, USA : , : John Wiley, , 2004 |
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ISBN |
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1-280-27232-5 |
9786610272327 |
0-470-86912-7 |
0-470-86911-9 |
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Descrizione fisica |
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1 online resource (ix, 271 pages) : illustrations |
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Collana |
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Novartis Foundation symposium ; ; 261 |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Pain - Molecular aspects |
Pain - Pathophysiology |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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"Symposium on Pathological pain: from molecular to clinical aspects, held at the Novartis Tsukuba Research Institute, Tsuskuba [sic], Japan, in collaboration with the Novartis Foundation (Japan) for the Promotion of Science, 30 September-2 October 2003; editors, Derek J. Chadwick (organizer) and Jamie Goode"--P. v. |
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Nota di bibliografia |
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Includes bibliographical references and indexes. |
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Nota di contenuto |
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PATHOLOGICAL PAIN: FROM MOLECULAR TO CLINICAL ASPECTS; Contents; Participants; Chair's introduction; Regulation mechanisms of vanilloid receptors; Discussion; Sodium channels and neuropathic pain; Discussion; Ion channel activities implicated in pathological pain; Discussion; General discussion I; Chronic pain and microglia: the role of ATP; Discussion; Neurotrophic influences on neuropathic pain; Discussion; Changes in DRG neurons and spinal excitability in neuropathy; Discussion; Functional reorganization of the spinal pain pathways in developmental and pathological conditions; Discussion |
Central plasticity in pathological pain; Discussion; General discussion II; Anti-opioid systems in morphine tolerance and addiction - locus-specific involvement of nociceptin and the NMDA receptor; Discussion; Chronic morphine-induced plasticity among signalling molecules; Discussion; Opioid tolerance and neuroplasticity; Discussion; General discussion III; A mechanism-based understanding of bone cancer pain; |
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Discussion; Mechanistic and clinical aspects of complex regional pain syndrome (CRPS); Discussion; Cortical pathophysiology of chronic pain; Discussion; Final discussion Translating basic research to the clinicIndex of contributors; Subject index |
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Sommario/riassunto |
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This book brings together contributions from key investigators in the area of pathological pain. It covers the molecular basis of receptors and channels involved in nociception, the possible messages that cause neuropathic plasticity, spinal plasticity in neuropathy, plastic changes in opioid systems in neuropathy and opioid tolerance, and plastic changes related to pathological pain. |
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