Corticotropin-releasing factor [[electronic resource] /] / [editors, Derek J. Chadwick, Joan Marsh, and Kate Ackrill]

• Record Nr.: UNINA9910144726803321
• Pubbl/distr/stampa: Chichester ; ; New York, : Wiley, 1993
• ISBN: 1-282-34783-7; 9786612347832; 0-470-51436-1; 0-470-51437-X
• Descrizione fisica: 1 online resource (370 p.)
• Collana: Ciba Foundation symposium ; ; 172
• Altri autori (Persone): ChadwickDerek; MarshJoan; AckrillKate
• Disciplina: 612.8; 612.8262
• Soggetti: Corticotropin releasing hormone; Electronic books.
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Symposium on Corticotropin-Releasing Factor, held at the Ciba Foundation, London, 10-12 March 1992.; "A Wiley-Interscience publication."
• Nota di bibliografia: Includes bibliographical references and indexes.
• Nota di contenuto: CORTICOTROPIN-RELEASING FACTOR; Contents; Introduction; The functional neuroanatomy of corticotropin-releasing factor; Second messenger regulation of mRNA for corticotropin- releasing factor; Central and feedback regulation of hypothalamic corticotropin-releasing factor secretion; Characterization and regulation of corticotropin-releasing factor receptors in the central nervous, endocrine and immune systems; Corticotropin-releasing factor and its binding protein In human plasma; The regulation of hypothalamic corticotropin-releasing factor release: in vitro studies; Intrahypothalamic neuroendocrine actions of corticotropin-releasing factorExpression of corticotropin-releasing factor mRNA in response to stress; General discussion : A consideration of methodology; Mechanisms mediating the effects of cytokines on neuroendocrine functions in the rat; Infection as a stressor: a cytokine-mediated ; activation of the hypothalamo-pituitary-adrenal axis?; Central actions of corticotropin-releasing factor on autonomic nervous activity and cardiovascular function; Peripheral anti-inflammatory actions of corticotropin-releasing factor; The role of corticotropin-releasing factor in behavioural responses to stressThe role of corticotropin-releasing factor in the pathophysiology of affective and anxiety disorders: laboratory and clinical studies; The role of corticotropin-releasing factor in the investigation of endocrine diseases; Final general discussion : Functional anatomy; Regulation of CRF; Immune aspects; Clinical aspects; Future directions; Index of contributors; Subject index
• Sommario/riassunto: Working on Corticotropin-Releasing Factor in a variety of systems, experts present a coherent depiction of this peptide's role in the control and coordination of the response to stress-inducing situations.